ins(3;7)(q26;q34q22) TRB/MECOM

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute myeloblastic leukemia with minimal differentiation (FAB type M0)

Genes Involved and Proteins

Gene name
TRB
Location
7q34
Gene name
MECOM
Location
3q26.2

Bibliography

Pubmed IDLast YearTitleAuthors
104829861999Activation of EVI1 transcripts with chromosomal translocation joining the TCRVbeta locus and the EVI1 gene in human acute undifferentiated leukemia cell line (Kasumi-3) with a complex translocation of der(3)t(3;7;8).Suzukawa K et al

Summary

Fusion gene

TRB/MECOM TRB (7q34) MECOM (3q26.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

ins(3;7)(q26;q34q22) TRB/MECOM

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3290/ins(3;7)(q26;q34q22)-trb-mecom