inv(14)(q11q32) BCL11B/TRD

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
BCL11B
Location
14q32.2
Gene name
TRD
Location
14q11.2

Bibliography

Pubmed IDLast YearTitleAuthors
156687002005Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL.Przybylski GK et al

Summary

Fusion gene

BCL11B/TRD BCL11B (14q32.2) TRD (14q11.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

inv(14)(q11q32) BCL11B/TRD

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2538/inv(14)(q11q32)-bcl11b-trd