t(1;8)(q31;p11) TPR/FGFR1

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Chronic myeloproliferative disorder, NOS

Genes Involved and Proteins

Gene name
TPR
Location
1q31.1
Gene name
FGFR1
Location
8p11.23

Highly cited references

Pubmed IDYearTitleCitations
263914362016Functional characterization, localization, and inhibitor sensitivity of the TPR-FGFR1 fusion in 8p11 myeloproliferative syndrome.4
250374432014Molecular identification of a TPR-FGFR1 fusion transcript in an adult with myeloproliferative neoplasm, T-lymphoblastic lymphoma, and a t(1;8)(q25;p11.2).2

Bibliography

Pubmed IDLast YearTitleAuthors
226191102012Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome.Li F et al
250374432014Molecular identification of a TPR-FGFR1 fusion transcript in an adult with myeloproliferative neoplasm, T-lymphoblastic lymphoma, and a t(1;8)(q25;p11.2).Kim SY et al

Summary

Fusion gene

TPR/FGFR1 TPR (1q31.1) FGFR1 (8p11.23)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(1;8)(q31;p11) TPR/FGFR1

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/1668/t(1;8)(q31;p11)-tpr-fgfr1