t(1;14)(p33;q11) TRD/TAL1

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
Location
14q11.2
Gene name
Location
1p33

Bibliography

Pubmed IDLast YearTitleAuthors
19645811990Two distinct mechanisms for the SCL gene activation in the t(1;14) translocation of T-cell leukemias.Bernard O et al
23030351990The tal gene undergoes chromosome translocation in T cell leukemia and potentially encodes a helix-loop-helix protein.Chen Q et al
27403411989Involvement of the TCL5 gene on human chromosome 1 in T-cell leukemia and melanoma.Finger LR et al
84123121993Characterization of translocation t(1;14)(p32;q11) in a T and in a B acute leukemia.Bernard O et al

Summary

Fusion gene

TRD/TAL1 TRD (14q11.2) TAL1 (1p33)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(1;14)(p33;q11) TRD/TAL1

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3297/t(1;14)(p33;q11)-trd-tal1