t(2;4)(p23;q21) SEC31A/ALK

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Diffuse large B-cell lymphoma

Genes Involved and Proteins

Gene name
Location
4q21.22
Gene name
Location
2p23.2

Highly cited references

Pubmed IDYearTitleCitations
202078482010ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions.25
257157712016SEC31A-ALK Fusion Gene in Lung Adenocarcinoma.15
211096912011Cytogenetically complex SEC31A-ALK fusions are recurrent in ALK-positive large B-cell lymphomas.13

Bibliography

Pubmed IDLast YearTitleAuthors
202078482010ALK-positive large B-cell lymphomas with cryptic SEC31A-ALK and NPM1-ALK fusions.Van Roosbroeck K et al
211096912011Cytogenetically complex SEC31A-ALK fusions are recurrent in ALK-positive large B-cell lymphomas.Bedwell C et al

Summary

Fusion gene

SEC31A/ALK SEC31A (4q21.22) ALK (2p23.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(2;4)(p23;q21) SEC31A/ALK

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3189/t(2;4)(p23;q21)-sec31a-alk