t(2;11)(q22;q21) CXCR4/MAML2

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Chronic lymphocytic leukemia

Genes Involved and Proteins

Gene name
CXCR4
Location
2q22.1
Gene name
MAML2
Location
11q21

Bibliography

Pubmed IDLast YearTitleAuthors
248552092014Translocation t(2;11) in CLL cells results in CXCR4/MAML2 fusion oncogene.Acunzo M et al

Summary

Fusion gene

CXCR4/MAML2 CXCR4 (2q22.1) MAML2 (11q21)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(2;11)(q22;q21) CXCR4/MAML2

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2643/t(2;11)(q22;q21)-cxcr4-maml2