t(3;11)(p24;p15) NUP98/TOP2B

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute monoblastic leukemia without differentiation (FAB type M5a)

Genes Involved and Proteins

Gene name
NUP98
Location
11p15.4
Gene name
TOP2B
Location
3p24.2

Highly cited references

Pubmed IDYearTitleCitations
161664242005NUP98 is fused to topoisomerase (DNA) IIbeta 180 kDa (TOP2B) in a patient with acute myeloid leukemia with a new t(3;11)(p24;p15).11

Bibliography

Pubmed IDLast YearTitleAuthors
161664242005NUP98 is fused to topoisomerase (DNA) IIbeta 180 kDa (TOP2B) in a patient with acute myeloid leukemia with a new t(3;11)(p24;p15).Nebral K et al

Summary

Fusion gene

NUP98/TOP2B NUP98 (11p15.4) TOP2B (3p24.2)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(3;11)(p24;p15) NUP98/TOP2B

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3042/t(3;11)(p24;p15)-nup98-top2b