t(5;9)(q23;q34) SNX2/ABL1

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
Location
5q23.2
Gene name
Location
9q34.12

Highly cited references

Pubmed IDYearTitleCitations
213919722011Identification of FOXP1 and SNX2 as novel ABL1 fusion partners in acute lymphoblastic leukaemia.11
242156202014Poor responses to tyrosine kinase inhibitors in a child with precursor B-cell acute lymphoblastic leukemia with SNX2-ABL1 chimeric transcript.7
243678932014Sensitivity of SNX2-ABL1 toward tyrosine kinase inhibitors distinct from that of BCR-ABL1.6
282787242017SNX2-ABL1-positive acute lymphoblastic leukemia possibly has a poor prognosis.0

Bibliography

Pubmed IDLast YearTitleAuthors
213919722011Identification of FOXP1 and SNX2 as novel ABL1 fusion partners in acute lymphoblastic leukaemia.Ernst T et al

Summary

Fusion gene

SNX2/ABL1 SNX2 (5q23.2) ABL1 (9q34.12)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(5;9)(q23;q34) SNX2/ABL1

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3223/t(5;9)(q23;q34)-snx2-abl1