Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(8;19)(p11;q13) KAT6A/LEUTX

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Atlas_Id 2856
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Acute myelomonocytic leukemia (FAB type M4)

Genes involved and Proteins

Gene NameKAT6A
Location 8p11.21
Gene NameLEUTX
Location 19q13.2


The leucine twenty homeobox (LEUTX) gene, which lacks a histone acetyltransferase domain, is fused to KAT6A in therapy-related acute myeloid leukemia with t(8;19)(p11;q13)
Chinen Y, Taki T, Tsutsumi Y, Kobayashi S, Matsumoto Y, Sakamoto N, Kuroda J, Horiike S, Nishida K, Ohno H, Uike N, Taniwaki M
Genes Chromosomes Cancer 2014 Apr;53(4):299-308
PMID 24446090

Translocations implicated (Data extracted from papers in the Atlas)

 t(8;19)(p11;q13) KAT6A/LEUTX

External links

KAT6A (8p11.21) LEUTX (19q13.2)

Mitelman databaset(8;19)(p11;q13)
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Mon Dec 14 18:28:13 CET 2020

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