Atlas of Genetics and Cytogenetics in Oncology and Haematology

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t(8;22)(q24;q11) IGL/PVT1

Written2018-01Jean-Loup Huret, Philippe Dessen

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Atlas_Id 2830
Note Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute

Clinics and Pathology

Disease Burkitt lymphoma/leukemia

Genes involved and Proteins

Gene NameIGL
Location 22q11.22
Gene NamePVT1
Location 8q24.21


Effects of translocations on transcription from PVT
Shtivelman E, Bishop JM
Mol Cell Biol 1990 Apr;10(4):1835-9
PMID 2181290
Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma
Shtivelman E, Henglein B, Groitl P, Lipp M, Bishop JM
Proc Natl Acad Sci U S A 1989 May;86(9):3257-60
PMID 2470097

Translocations implicated (Data extracted from papers in the Atlas)

 t(8;22)(q24;q11) IGL/PVT1

External links

IGL (22q11.22) PVT1 (8q24.21)

Mitelman databaset(8;22)(q24;q11) [Case List]    t(8;22)(q24;q11) [Transloc-MCList] IGL/PVT1 [Fusion-MCList]
COSMICHisto = - Site = haematopoietic_and_lymphoid_tissue (COSMIC)
arrayMap (UZH-SIB Zurich)[select an item]
REVIEW articlesautomatic search in PubMed
Last year articlesautomatic search in PubMed
All articlesautomatic search in PubMed

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indexed on : Wed Mar 11 20:44:32 CET 2020

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