CDKN2A/MTAP (9p21)

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Acute lymphoblastic leukemia/lymphoblastic lymphoma

Genes Involved and Proteins

Gene name
Location
9p21.3
Gene name
Location
9p21.3

Highly cited references

Pubmed IDYearTitleCitations
200818102010CDKN2A and MTAP deletions in peritoneal mesotheliomas are correlated with loss of p16 protein expression and poor survival.23
331557732020Loss of CDKN2A at chromosome 9 has a poor clinical prognosis and promotes lung cancer progression.4
224933552012Molecular characterization of human cutaneous melanoma-derived cell lines.3
351578292022Abemaciclib in patients with p16ink4A-deficient mesothelioma (MiST2): a single-arm, open-label, phase 2 trial.1

Bibliography

Pubmed IDLast YearTitleAuthors
233346682013The genomic landscape of hypodiploid acute lymphoblastic leukemia.Holmfeldt L et al

Summary

Fusion gene

CDKN2A/MTAP CDKN2A (9p21.3) MTAP (9p21.3)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Citation

Philippe Dessen ; Jean-Loup Huret

CDKN2A/MTAP (9p21)

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2593/cdkn2a-mtap-(9p21)