t(11;16)(q23;p13) KMT2A/MYH11

2018-01-01   Jean-Loup Huret , Philippe Dessen 

Clinics and Pathology

Disease

Acute myeloid leukemia, NOS|Refractory anemia with excess blasts-2

Genes Involved and Proteins

Gene name
KMT2A
Location
11q23.3
Gene name
MYH11
Location
16p13.11

Bibliography

Pubmed IDLast YearTitleAuthors
236289582013The MLL recombinome of acute leukemias in 2013.Meyer C et al
255526802015RNA sequencing reveals a unique fusion of the lysine (K)-specific methyltransferase 2A and smooth muscle myosin heavy chain 11 in myelodysplastic syndrome and acute myeloid leukemia.Sanders MA et al

Summary

Fusion gene

KMT2A/MYH11 KMT2A (11q23.3) MYH11 (16p13.11)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Jean-Loup Huret ; Philippe Dessen

t(11;16)(q23;p13) KMT2A/MYH11

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/2888/t(11;16)(q23;p13)-kmt2a-myh11