t(14;16)(q32;q24) IGH/IRF8

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Diffuse large B-cell lymphoma

Genes Involved and Proteins

Gene name
Location
14q32.33
Gene name
Location
16q24.1

Highly cited references

Pubmed IDYearTitleCitations
298992972018Molecular Mechanisms of Disease Progression in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type during Ibrutinib Therapy.6

Bibliography

Pubmed IDLast YearTitleAuthors
235738292014IRF8 is associated with germinal center B-cell-like type of diffuse large B-cell lymphoma and exceptionally involved in translocation t(14;16)(q32.33;q24.1).Tinguely M et al
237757152013A capture-sequencing strategy identifies IRF8, EBF1, and APRIL as novel IGH fusion partners in B-cell lymphoma.Bouamar H et al

Summary

Fusion gene

IGH/IRF8 IGH (14q32.33) IRF8 (16q24.1)

Note

Non-annotated chromosomal abnormality. Preliminary data :
if you are an author who wish to write a full paper/card on this translocation,go to  How to contribute

Citation

Philippe Dessen ; Jean-Loup Huret

t(14;16)(q32;q24) IGH/IRF8

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/1669/t(14;16)(q32;q24)-igh-irf8