Identity |
ICD-Topo | C420,C421,C424 BLOOD, BONE MARROW, & HEMATOPOIETIC SYS |
Atlas_Id | 3182 |
Note | Non-annotated chromosomal abnormality. Preliminary data : if you are an author who wish to write a full paper/card on this translocation, go to  How to contribute |
Clinics and Pathology |
Disease | Chronic myelomonocytic leukemia |
Genes involved and Proteins |
Gene Name | RUNX1 |
Location | 21q22.12 |
Gene Name | UBL7 |
Location | 15q24.1 |
Bibliography |
t(15;21) translocations leading to the concurrent downregulation of RUNX1 and its transcription factor partner genes SIN3A and TCF12 in myeloid disorders |
L'Abbate A, Tolomeo D, De Astis F, Lonoce A, Lo Cunsolo C, Mühlematter D, Schoumans J, Vandenberghe P, Van Hoof A, Palumbo O, Carella M, Mazza T, Storlazzi CT |
Mol Cancer 2015 Dec 16;14:211 |
PMID 26671595 |
Translocations implicated (Data extracted from papers in the Atlas) |
t(15;21)(q24;q22) RUNX1/UBL7 | |
External links |
Mitelman database | t(15;21)(q24;q22) |
COSMIC | Histo = - Site = haematopoietic_and_lymphoid_tissue (COSMIC) |
arrayMap (UZH-SIB Zurich) | [select an item] |
REVIEW articles | automatic search in PubMed |
Last year articles | automatic search in PubMed |
All articles | automatic search in PubMed |
© Atlas of Genetics and Cytogenetics in Oncology and Haematology | indexed on : Mon Dec 14 18:29:05 CET 2020 |
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