t(15;21)(q24;q22) RUNX1/UBL7

2018-01-01   Philippe Dessen , Jean-Loup Huret 

Clinics and Pathology

Disease

Chronic myelomonocytic leukemia

Genes Involved and Proteins

Gene name
RUNX1
Location
21q22.12
Gene name
UBL7
Location
15q24.1

Bibliography

Pubmed IDLast YearTitleAuthors
266715952015t(15;21) translocations leading to the concurrent downregulation of RUNX1 and its transcription factor partner genes SIN3A and TCF12 in myeloid disorders.L'Abbate A et al

Summary

Fusion gene

RUNX1/UBL7 RUNX1 (21q22.12) UBL7 (15q24.1)

Note

Non-annotated chromosomal abnormality. Preliminary data :
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Citation

Philippe Dessen ; Jean-Loup Huret

t(15;21)(q24;q22) RUNX1/UBL7

Atlas Genet Cytogenet Oncol Haematol. 2018-01-01

Online version: http://atlasgeneticsoncology.org/haematological/3182/t(15;21)(q24;q22)-runx1-ubl7