Deep Insights

Inhibitors of the heat shock protein 90: from cancer clinical trials to neurodegenerative diseases
Jean François Peyrat, Samir Messaoudi, Jean Daniel Brion, Mouad Alami

LDI-PCR in Cancer Translocation Mapping
Björn Schneider, Hans G Drexler, Roderick AF MacLeod

The roles of SRA1 gene in breast cancer
Yi Yan, Charlton Cooper, Etienne Leygue

Glutathione S-Transferase pi (GSTP1)
Isabelle Meiers

Ubiquitin, ubiquitination and the ubiquitin-proteasome system in cancer
Ioannis A Voutsadakis

TGFβ and Bim: Partners in cell death
Gary M Wildey, Philip H Howe

Role of TWIST proteins in cancer progression
Jérémy Bastid, Claire Ciancia, Alain Puisieux, Stéphane Ansieau

Caspase-8 and Cancer
Simone Fulda

RLN2 and its role in cancer
Jordan M Willcox, Alastair JS Summerlee

Dynamics and plasticity of chromosome ends: consequences in human pathologies
Caroline Schluth-Bolard, Alexandre Ottaviani, Amadou Bah, Amina Boussouar, Eric Gilson and Frédérique Magdinier

Detection of minimal residual disease in acute lymphoblastic leukemia
Dario Campana

The IKK-related kinases, unsuspected culprits in oncogenesis?
Marc J Servant, Jean-François Clément, Sylvain Meloche

Mapping of Structure-Function Peptide Sites on the Human Alpha-fetoprotein Amino Acid Sequence
Gerald J. Mizejewski

The HLA-G non classical MHC class I molecule is expressed in cancer with poor prognosis. Implications in tumour escape from immune system and clinical applications
Catherine Menier, Nathalie Rouas-Freiss, Edgardo D Carosella

RET point mutations in Thyroid Carcinoma
Rossella Elisei, Cristina Romei, Barbara Cosci, Eleonora Molinaro, Laura Agate, Valeria Bottici, Aldo Pinchera

JAK2 mutations in myeloproliferative neoplasms
Naseema Gangat and Ayalew Tefferi

Roles of tetraspanin proteins in cell and tumor biology
Pedro A Lazo

A role of actin-to-CD95 connection in CD-95 apoptotic pathway
Daria Brambilla, Francesco Lozupone, Stefano Fais

Genetic Instability in Cancer
Sheron Perera, BSc and Bharati Bapat, PhD

Hepatocarcinogenesis
Raphael Saffroy, Antoinette Lemoine, Brigitte Debuire

Three-dimensional organization of the mammalian nucleus in normal and tumor cells
Sabine Mai

MLL: Deep Insight
Jay L. Hess M.D. Ph.D.

Ethical issues in cancer genetics
Robert Roger Lebel, MD, FACMG

Spatial arrangement of the human genome and its possible functional role
Stanislav Kozubek

Genomic Imprinting: Parental differentiation of the genome
Keith Killian

Cancer cytogenetics update 2005
Felix Mitelman

The nuclear pore complex becomes alive: new insights into its dynamics and involvement in different cellular processes
Joachim Köser, Bohumil Maco, Ueli Aebi, and Birthe Fahrenkrog

The vagaries of non-traditional mendelian recessive inheritance in uniparental disomy: AA x Aa = aa !
Eric Engel

Monitoring of minimal residual disease in acute myeloid leukemia
Wolfgang Kern, Susanne Schnittger, Claudia Schoch, Torsten Haferlach

"Deep insight" into microarray technology
Claudia Schoch, Martin Dugas, Wolfgang Kern, Alexander Kohlmann, Susanne Schnittger, Torsten Haferlach

Some lessons from uniparental disomy (UDP) in the framework of comtemporary cytogenetics and molecular biology.
E. Engel M.D

Comparative Cancer Cytogenetics
Nicole McNeil, Cristina Montagna, Michael J. Difilippantonio and Thomas Ried

The WNT Signaling Pathway and Its Role in Human Solid Tumors
Lin Thorstensen and Ragnhild A. Lothe

Heterochromatin, from Chromosome to Protein
Marie-Geneviève Mattei and Judith Luciani

Transcription factors
Valentina Guasconi, Hakima Yahi, Slimane Ait-Si-Ali

Genome and society
Axel Kahn

Functional organization of the genome: chromatin
Patricia Ridgway, Christèle Maison, Geneviève Almouzni.

Ataxia-Telangiectasia and variants
Nancy Uhrhammer, Jacques-Olivier Bay, Susan Perlman, Richard A Gatti.

The Fas - Fas Ligand apoptotic pathway
Pierre Bobé.

Deregulation of genetic pathways in neuroendocrine tumors
Alain Calender.

Upstream Signal Transduction of NF-kB Activation
Fei Chen, Jacquelyn Bower, Laurence M. Demers, Xianglin Sh.

Ring chromosomes: vicious circles at the end and beginning of life
David Gisselsson.

Chromosomal Instability in Cancer: Causes and Consequences
David Gisselsson.

Tying up Loose Ends: Generation and Repair of DNA Double-Strand Breaks
Julianne Smith, Kathleen Smith, Christine Mézard.

Nucleotide excision repair
Leon H.F. Mullenders, Anne Stary, Alain Sarasin.

Classification of T-cell disorders
Vasantha Brito-Babapulle, Estella Matutes, Daniel Catovsky.

Micronuclei : Pitfalls and Problems
John R K Savage.

Classification of B-cell chronic lymphoproliferative disorders (CLD): cytogenetic entities, immunopheneotype and clinical features
Antonio Cuneo.

Classification of B-cell non-Hodgkin’s lymphomas (NHL) : cytogenetic entities, immunopheneotype and clinical features
Antonio Cuneo.

Familial chronic lymphocytic leukaemia
Martin Yuille.

Minimal residual disease in acute lymphoblastic Leukemia
Hélène Cavé.

RAS family
Franz Watzinger, Thomas Lion.

An Introduction to Chromosomal Aberrations
John R K Savage.