| Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene. |
| von Lindern M, van Baal S, Wiegant J, Raap A, Hagemeijer A, Grosveld G |
| Molecular and cellular biology. 1992 ; 12 (8) : 3346-3355. |
| PMID 1630450 |
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| Characterization of the translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia. |
| von Lindern M, Breems D, van Baal S, Adriaansen H, Grosveld G |
| Genes, chromosomes & cancer. 1992 ; 5 (3) : 227-234. |
| PMID 1384675 |
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| The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA. |
| von Lindern M, Fornerod M, van Baal S, Jaegle M, de Wit T, Buijs A, Grosveld G |
| Molecular and cellular biology. 1992 ; 12 (4) : 1687-1697. |
| PMID 1549122 |
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| The human CAN protein, a putative oncogene product associated with myeloid leukemogenesis, is a nuclear pore complex protein that faces the cytoplasm. |
| Kraemer D, Wozniak RW, Blobel G, Radu A |
| Proceedings of the National Academy of Sciences of the United States of America. 1994 ; 91 (4) : 1519-1523. |
| PMID 8108440 |
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| Relocation of the carboxyterminal part of CAN from the nuclear envelope to the nucleus as a result of leukemia-specific chromosome rearrangements. |
| Fornerod M, Boer J, van Baal S, Jaeglˆ© M, von Lindern M, Murti KG, Davis D, Bonten J, Buijs A, Grosveld G |
| Oncogene. 1995 ; 10 (9) : 1739-1748. |
| PMID 7753551 |
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| Interaction of cellular proteins with the leukemia specific fusion proteins DEK-CAN and SET-CAN and their normal counterpart, the nucleoporin CAN. |
| Fornerod M, Boer J, van Baal S, Morreau H, Grosveld G |
| Oncogene. 1996 ; 13 (8) : 1801-1808. |
| PMID 8895527 |
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| G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214. |
| van Deursen J, Boer J, Kasper L, Grosveld G |
| The EMBO journal. 1996 ; 15 (20) : 5574-5583. |
| PMID 8896451 |
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| The nucleoporin CAN/Nup214 binds to both the cytoplasmic and the nucleoplasmic sides of the nuclear pore complex in overexpressing cells. |
| Boer JM, van Deursen JM, Croes HJ, Fransen JA, Grosveld GC |
| Experimental cell research. 1997 ; 232 (1) : 182-185. |
| PMID 9141635 |
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| Function and assembly of nuclear pore complex proteins. |
| Bodoor K, Shaikh S, Enarson P, Chowdhury S, Salina D, Raharjo WH, Burke B |
| Biochemistry and cell biology = Biochimie et biologie cellulaire. 1999 ; 77 (4) : 321-329. |
| PMID 10546895 |
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| Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis. |
| Boer J, Bonten-Surtel J, Grosveld G |
| Molecular and cellular biology. 1998 ; 18 (3) : 1236-1247. |
| PMID 9488438 |
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| Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia. |
| Graux C, Cools J, Melotte C, Quentmeier H, Ferrando A, Levine R, Vermeesch JR, Stul M, Dutta B, Boeckx N, Bosly A, Heimann P, Uyttebroeck A, Mentens N, Somers R, MacLeod RA, Drexler HG, Look AT, Gilliland DG, Michaux L, Vandenberghe P, Wlodarska I, Marynen P, Hagemeijer A |
| Nature genetics. 2004 ; 36 (10) : 1084-1089. |
| PMID 15361874 |
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| Aberrant intracellular localization of SET-CAN fusion protein, associated with a leukemia, disorganizes nuclear export. |
| Saito S, Miyaji-Yamaguchi M, Nagata K |
| International journal of cancer. Journal international du cancer. 2004 ; 111 (4) : 501-507. |
| PMID 15239126 |
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| NUP214-ABL1 amplification in t(5;14)/HOX11L2-positive ALL present with several forms and may have a prognostic significance. |
| Ballerini P, Busson M, Fasola S, van den Akker J, Lapillonne H, Romana SP, Marynen P, Bernard OA, Landman-Parker J, Berger R |
| Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2005 ; 19 (3) : 468-470. |
| PMID 15674415 |
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| DEK-CAN molecular monitoring of myeloid malignancies could aid therapeutic stratification. |
| Garˆßon L, Libura M, Delabesse E, Valensi F, Asnafi V, Berger C, Schmitt C, Leblanc T, Buzyn A, Macintyre E |
| Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2005 ; 19 (8) : 1338-1344. |
| PMID 15973457 |
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| Fusion of NUP214 to ABL1 on amplified episomes in T-ALL--implications for treatment. |
| Stergianou K, Fox C, Russell NH |
| Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K. 2005 ; 19 (9) : 1680-1681. |
| PMID 16015385 |
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