Identity
HGNC
LOCATION
9p21.1
LOCUSID
ALIAS
ACONS,HEL60,IREB1,IREBP,IREBP1,IRP1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 48
MIM: 100880
HGNC: 117
Ensembl: ENSG00000122729
Variants:
dbSNP: 48
ClinVar: 48
TCGA: ENSG00000122729
COSMIC: ACO1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35121990 | 2022 | ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1. | 48 |
| 36142654 | 2022 | Human IRP1 Translocates to the Nucleus in a Cell-Specific and Iron-Dependent Manner. | 0 |
| 35121990 | 2022 | ENO1 suppresses cancer cell ferroptosis by degrading the mRNA of iron regulatory protein 1. | 48 |
| 36142654 | 2022 | Human IRP1 Translocates to the Nucleus in a Cell-Specific and Iron-Dependent Manner. | 0 |
| 34572542 | 2021 | The Iron Maiden. Cytosolic Aconitase/IRP1 Conformational Transition in the Regulation of Ferritin Translation and Iron Hemostasis. | 2 |
| 34572542 | 2021 | The Iron Maiden. Cytosolic Aconitase/IRP1 Conformational Transition in the Regulation of Ferritin Translation and Iron Hemostasis. | 2 |
| 32199885 | 2020 | Cellular iron sensing and regulation: Nuclear IRP1 extends a classic paradigm. | 7 |
| 32327693 | 2020 | Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis. | 16 |
| 32199885 | 2020 | Cellular iron sensing and regulation: Nuclear IRP1 extends a classic paradigm. | 7 |
| 32327693 | 2020 | Predicted loss and gain of function mutations in ACO1 are associated with erythropoiesis. | 16 |
| 28762519 | 2018 | Pathological changes in Sertoli cells and dysregulation of divalent metal transporter 1 with iron responsive element in the testes of idiopathic azoospermia patients. | 2 |
| 29330752 | 2018 | Evaluation of the iron regulatory protein-1 interactome. | 5 |
| 30415773 | 2018 | The roles of hypoxia-inducible Factor-1 and iron regulatory protein 1 in iron uptake induced by acute hypoxia. | 15 |
| 28762519 | 2018 | Pathological changes in Sertoli cells and dysregulation of divalent metal transporter 1 with iron responsive element in the testes of idiopathic azoospermia patients. | 2 |
| 29330752 | 2018 | Evaluation of the iron regulatory protein-1 interactome. | 5 |
Citation
Dessen P
ACO1 (aconitase 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-07-01
Online version: http://atlasgeneticsoncology.org/gene/47648/aco1
