ACOD1 (aconitate decarboxylase 1)

2016-03-01  

Identity

HGNC
ACOD1
LOCATION
13q22.3
LOCUSID
730249
ALIAS
CAD,IRG1

Other Information

Locus ID:

NCBI: 730249
MIM: 615275
HGNC: 33904
Ensembl: ENSG00000102794

Variants:

dbSNP: 730249
ClinVar: 730249
TCGA: ENSG00000102794
COSMIC: ACOD1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000102794ENST00000377462A6NK06
ENSG00000102794ENST00000449753H7C1Q4

Expression (GTEx)

0
1
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
N/A

References

Pubmed IDYearTitleCitations
236094502013Immune responsive gene 1 (IRG1) promotes endotoxin tolerance by increasing A20 expression in macrophages through reactive oxygen species.38
268723352016Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages.15
268723352016Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages.15
268723352016Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages.15
268723352016Gene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages.15
214245862011Expression profile of human immune-responsive gene 1 and generation and characterization of polyclonal antiserum.0
236103932013Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.0
236103932013Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production.0
252160592014Immune responsive gene 1, a novel oncogene, increases the growth and tumorigenicity of glioma.0
272525322016Suppression of IRG-1 Reduces Inflammatory Cell Infiltration and Lung Injury in Respiratory Syncytial Virus Infection by Reducing Production of Reactive Oxygen Species.0

Citation

Dessen P

ACOD1 (aconitate decarboxylase 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-03-01

Online version: http://atlasgeneticsoncology.org/gene/55679/acod1