ACOT11 (acyl-CoA thioesterase 11)

2014-11-01  

Identity

HGNC
LOCATION
1p32.3
LOCUSID
ALIAS
BFIT,STARD14,THEA,THEM1
FUSION GENES

Other Information

Locus ID:

NCBI: 26027
MIM: 606803
HGNC: 18156
Ensembl: ENSG00000162390

Variants:

dbSNP: 26027
ClinVar: 26027
TCGA: ENSG00000162390
COSMIC: ACOT11

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000162390ENST00000343744Q8WXI4
ENSG00000162390ENST00000371316Q8WXI4

Expression (GTEx)

0
1
2
3
4
5
6
7
8

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Fatty Acyl-CoA BiosynthesisREACTOMER-HSA-75105

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
116960002001BFIT, a unique acyl-CoA thioesterase induced in thermogenic brown adipose tissue: cloning, organization of the human gene and assessment of a potential link to obesity.22
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11
228971362012Human brown fat inducible thioesterase variant 2 cellular localization and catalytic function.5

Citation

Dessen P

ACOT11 (acyl-CoA thioesterase 11)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60087/acot11