Identity
HGNC
LOCATION
17q25.3
LOCUSID
ALIAS
ACT,ACTG,DFNA20,DFNA26,HEL-176
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 71
MIM: 102560
HGNC: 144
Ensembl: ENSG00000184009
Variants:
dbSNP: 71
ClinVar: 71
TCGA: ENSG00000184009
COSMIC: ACTG1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA446975 | Neurotoxicity Syndromes | Disease | ClinicalAnnotation | associated | PD | ||
| PA451879 | vincristine | Chemical | ClinicalAnnotation | associated | PD |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37368839 | 2023 | Bioinformatic identification and experiment validation revealed that ACTG1 is a promising prognostic signature and therapeutic target for sepsis. | 0 |
| 37542027 | 2023 | Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1. | 10 |
| 37368839 | 2023 | Bioinformatic identification and experiment validation revealed that ACTG1 is a promising prognostic signature and therapeutic target for sepsis. | 0 |
| 37542027 | 2023 | Exosomal PGAM1 promotes prostate cancer angiogenesis and metastasis by interacting with ACTG1. | 10 |
| 34856725 | 2022 | Actin gamma 1 is a critical regulator of pancreatic ductal adenocarcinoma. | 2 |
| 35054877 | 2022 | De Novo ACTG1 Variant Expands the Phenotype and Genotype of Partial Deafness and Baraitser-Winter Syndrome. | 2 |
| 34856725 | 2022 | Actin gamma 1 is a critical regulator of pancreatic ductal adenocarcinoma. | 2 |
| 35054877 | 2022 | De Novo ACTG1 Variant Expands the Phenotype and Genotype of Partial Deafness and Baraitser-Winter Syndrome. | 2 |
| 33545632 | 2021 | ACTG1 regulates intervertebral disc degeneration via the NF-κB-p65 and Akt pathways. | 4 |
| 34440452 | 2021 | Benefits of Exome Sequencing in Children with Suspected Isolated Hearing Loss. | 6 |
| 34767732 | 2021 | Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway. | 8 |
| 33545632 | 2021 | ACTG1 regulates intervertebral disc degeneration via the NF-κB-p65 and Akt pathways. | 4 |
| 34440452 | 2021 | Benefits of Exome Sequencing in Children with Suspected Isolated Hearing Loss. | 6 |
| 34767732 | 2021 | Silencing ACTG1 Expression Induces Prostate Cancer Epithelial Mesenchymal Transition Through MAPK/ERK Signaling Pathway. | 8 |
| 32028042 | 2020 | Previously undescribed phenotypic findings and novel ACTG1 gene pathogenic variants in Baraitser-Winter cerebrofrontofacial syndrome. | 4 |
Citation
Dessen P
ACTG1 (actin gamma 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-11-01
Online version: http://atlasgeneticsoncology.org/gene/561/actg1
