ACTR8 (actin related protein 8)

2011-06-01  

Identity

HGNC
ACTR8
LOCATION
3p21.1
LOCUSID
93973
ALIAS
ARP8,INO80N,hArp8
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 93973
HGNC: 14672
Ensembl: ENSG00000113812

Variants:

dbSNP: 93973
ClinVar: 93973
TCGA: ENSG00000113812
COSMIC: ACTR8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000113812ENST00000335754Q9H981
ENSG00000113812ENST00000482349Q9H981
ENSG00000113812ENST00000486794H0Y849
ENSG00000113812ENST00000498740C9J7L6

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
DNA RepairREACTOMER-HSA-73894
Nucleotide Excision RepairREACTOMER-HSA-5696398
Global Genome Nucleotide Excision Repair (GG-NER)REACTOMER-HSA-5696399
DNA Damage Recognition in GG-NERREACTOMER-HSA-5696394
DeubiquitinationREACTOMER-HSA-5688426
UCH proteinasesREACTOMER-HSA-5689603

References

Pubmed IDYearTitleCitations
229771802012Structure of Actin-related protein 8 and its contribution to nucleosome binding.28
209710672010The mammalian INO80 complex is recruited to DNA damage sites in an ARP8 dependent manner.27
181639882008The actin-related protein hArp8 accumulates on the mitotic chromosomes and functions in chromosome alignment.16
252996022014DNA binding properties of the actin-related protein Arp8 and its role in DNA repair.7
210480312011Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.5

Citation

Dessen P

ACTR8 (actin related protein 8)

Atlas Genet Cytogenet Oncol Haematol. 2011-06-01

Online version: http://atlasgeneticsoncology.org/gene/52229/actr8