Identity
HGNC
LOCATION
16q23.1
LOCUSID
ALIAS
ADAMTS21,KNO2,MMCAT
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 170692
MIM: 607512
HGNC: 17110
Ensembl: ENSG00000140873
Variants:
dbSNP: 170692
ClinVar: 170692
TCGA: ENSG00000140873
COSMIC: ADAMTS18
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000140873 | ENST00000282849 | Q8TE60 |
| ENSG00000140873 | ENST00000449265 | B4DEX3 |
| ENSG00000140873 | ENST00000562332 | H3BMG1 |
| ENSG00000140873 | ENST00000562345 | H3BTZ3 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38199772 | 2024 | [A family with developmental glaucoma and microcornea due to novel ADAMTS18 gene mutations]. | 0 |
| 38199772 | 2024 | [A family with developmental glaucoma and microcornea due to novel ADAMTS18 gene mutations]. | 0 |
| 36632911 | 2023 | Secreted protease ADAMTS18 in development and disease. | 5 |
| 36632911 | 2023 | Secreted protease ADAMTS18 in development and disease. | 5 |
| 33469885 | 2021 | Aberrant methylation of the 16q23.1 tumor suppressor gene ADAMTS18 promotes tumorigenesis and progression of clear cell renal cell carcinoma. | 4 |
| 34320216 | 2021 | Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis. | 8 |
| 33469885 | 2021 | Aberrant methylation of the 16q23.1 tumor suppressor gene ADAMTS18 promotes tumorigenesis and progression of clear cell renal cell carcinoma. | 4 |
| 34320216 | 2021 | Characterization of a functional endothelial super-enhancer that regulates ADAMTS18 and angiogenesis. | 8 |
| 32218432 | 2020 | The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche. | 21 |
| 32218432 | 2020 | The secreted protease Adamts18 links hormone action to activation of the mammary stem cell niche. | 21 |
| 30417422 | 2019 | Inactivation of ADAMTS18 by aberrant promoter hypermethylation contribute to lung cancer progression. | 9 |
| 30417422 | 2019 | Inactivation of ADAMTS18 by aberrant promoter hypermethylation contribute to lung cancer progression. | 9 |
| 28362704 | 2018 | Downregulation of ADAMTS18 May Serve as a Poor Prognostic Biomarker for Cervical Cancer Patients. | 5 |
| 28362704 | 2018 | Downregulation of ADAMTS18 May Serve as a Poor Prognostic Biomarker for Cervical Cancer Patients. | 5 |
| 28503860 | 2017 | Epigenetic silencing of ADAMTS18 promotes cell migration and invasion of breast cancer through AKT and NF-κB signaling. | 15 |
Citation
Dessen P
ADAMTS18 (ADAM metallopeptidase with thrombospondin type 1 motif 18)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47184/adamts18
