ADGRB1 (adhesion G protein-coupled receptor B1)

2003-02-01  

Identity

HGNC
LOCATION
8q24.3
LOCUSID
ALIAS
BAI1,GDAIF
FUSION GENES

Other Information

Locus ID:

NCBI: 575
MIM: 602682
HGNC: 943
Ensembl: ENSG00000181790

Variants:

dbSNP: 575
ClinVar: 575
TCGA: ENSG00000181790
COSMIC: ADGRB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181790ENST00000323289O14514
ENSG00000181790ENST00000517894O14514
ENSG00000181790ENST00000521208E5RG74
ENSG00000181790ENST00000643448A0A2R8Y5M7

Expression (GTEx)

0
10
20
30
40
50
60
70

Pathways

PathwaySourceExternal ID
p53 signaling pathwayKEGGko04115
p53 signaling pathwayKEGGhsa04115

References

Pubmed IDYearTitleCitations
235957542013The adhesion-GPCR BAI1 regulates synaptogenesis by controlling the recruitment of the Par3/Tiam1 polarity complex to synaptic sites.52
125078862003Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression.36
237826962013Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.34
217245862011Overexpression of MBD2 in glioblastoma maintains epigenetic silencing and inhibits the antiangiogenic function of the tumor suppressor gene BAI1.28
267108502016Stalk-dependent and Stalk-independent Signaling by the Adhesion G Protein-coupled Receptors GPR56 (ADGRG1) and BAI1 (ADGRB1).27
223301402012A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1.22
120748422002Brain-specific angiogenesis inhibitor 1 (BAI1) is expressed in human cerebral neuronal cells.18
245099092014Brain angiogenesis inhibitor 1 is expressed by gastric phagocytes during infection with Helicobacter pylori and mediates the recognition and engulfment of human apoptotic gastric epithelial cells.13
118757202002Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis.10
253766072015Changes in BAI1 and nestin expression are prognostic indicators for survival and metastases in breast cancer and provide opportunities for dual targeted therapies.9

Citation

Dessen P

ADGRB1 (adhesion G protein-coupled receptor B1)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/749/adgrb1