Atlas of Genetics and Cytogenetics in Oncology and Haematology

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ADH7 (alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide)

Identity

Other namesADH4
HGNC (Hugo) ADH7
LocusID (NCBI) 131
Location 4q23
Location_base_pair Starts at 100333418 and ends at 100356667 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ADH7   256
Entrez_Gene (NCBI)ADH7  131  alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
Cards
GeneCards (Weizmann)ADH7
Ensembl (Hinxton)ENSG00000196344 [Gene_View]  chr4:100333418-100356667 [Contig_View]  ADH7 [Vega]
AceView (NCBI)ADH7
Genatlas (Paris)ADH7
SOURCE (Stanford)NM_000673 NM_001166504
Genomic and cartography
GoldenPath (UCSC)ADH7  -  4q23   chr4:100333418-100356667 -  4q23   [Description]    (hg19-Feb_2009)
EnsemblADH7 - 4q23 [CytoView]
Mapping of homologs : NCBIADH7 [Mapview]
OMIM600086   
Gene and transcription
Genbank (Entrez)AK223472 AK301657 AK301696 AK310811 AK312854
RefSeq transcript (SRS)NM_000673 NM_001166504
RefSeq transcript (Entrez)NM_000673 NM_001166504
RefSeq genomic (SRS)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838915 NW_004078021
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838915 NW_004078021
Consensus coding sequences : CCDS (NCBI)ADH7
Cluster EST : UnigeneHs.389 [ SRS ] Hs.389 [ NCBI ]
CGAP (NCI)Hs.389
Alternative Splicing : Fast-db (Paris)GSHG0023426
Alternative Splicing GalleryENSG00000196344
Gene ExpressionADH7 [ NCBI-GEO ]   ADH7 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP40394 (SRS) P40394 (Uniprot)
NextProtP40394
With graphics : InterProP40394
Splice isoforms : SwissVarP40394(Swissvar)
Domaine pattern : Prosite (SRS)ADH_ZINC (PS00059)   
Domaine pattern : Prosite (Expaxy)ADH_ZINC (PS00059)   
Domains : Interpro (SRS)ADH_C    ADH_GroES-like    ADH_SF_Zn-type    ADH_Zn_CS    GroES-like    NAD(P)-bd_dom   
Domains : Interpro (EBI)ADH_C    ADH_GroES-like    ADH_SF_Zn-type    ADH_Zn_CS    GroES-like    NAD(P)-bd_dom   
Related proteins : CluSTrP40394
Domain families : Pfam (SRS)ADH_N (PF08240)    ADH_zinc_N (PF00107)   
Domain families : Pfam (Sanger)ADH_N (PF08240)    ADH_zinc_N (PF00107)   
Domain families : Pfam (NCBI)pfam08240    pfam00107   
DMDM131
Blocks (Seattle)P40394
PDB (SRS)1AGN    1D1S    1D1T   
PDB (PDBSum)1AGN    1D1S    1D1T   
PDB (IMB)1AGN    1D1S    1D1T   
PDB (RSDB)1AGN    1D1S    1D1T   
Human Protein AtlasENSG00000196344
HPRD02515
IPIIPI00872487   IPI00908386   IPI00945694   IPI00946812   
Protein Interaction databases
DIP (DOE-UCLA)P40394
IntAct (EBI)P40394
FunCoupENSG00000196344
REACTOMEADH7
Protein Interaction Database131
BioGRIDADH7
InParanoidP40394
Interologous Interaction database P40394
IntegromeDBADH7
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ADH7
SNP (GeneSNP Utah)ADH7
SNP : HGBaseADH7
Genetic variants : HAPMAPADH7
Somatic Mutations in Cancer : COSMICADH7 
CONAN: Copy Number AnalysisADH7 
Mutations and Diseases : HGMDADH7
OMIM600086   
GENETests600086   
Disease Genetic AssociationADH7
Huge Navigator ADH7 [HugePedia]  ADH7 [HugeCancerGEM]
Genomic VariantsADH7  ADH7 [DGVbeta]
snp3D : Map Gene to Disease131
General knowledge
Homologs : HomoloGeneADH7
Homology/Alignments : Family Browser (UCSC)ADH7
Phylogenetic Trees/Animal Genes : TreeFamADH7
Catalytic activity : Enzyme1.1.1.1 [ Enzyme-Expasy ]   1.1.1.1 [ Enzyme-SRS ]   1.1.1.1 [ IntEnz-EBI ]   1.1.1.1 [ BRENDA ]   1.1.1.1 [ KEGG ]   
Chemical/Protein Interactions : CTD131
Chemical/Pharm GKB GenePA24577
Clinical trialADH7
Cancer Resource (Charite)ENSG00000196344
Ontology : AmiGOretinoid metabolic process  alcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  aldehyde oxidase activity  retinol dehydrogenase activity  extracellular region  nucleolus  cytoplasm  cytosol  ethanol catabolic process  ethanol oxidation  ethanol oxidation  xenobiotic metabolic process  zinc ion binding  response to bacterium  fatty acid omega-oxidation  retinol binding  ethanol binding  retinol metabolic process  retinoic acid metabolic process  protein homodimerization activity  small molecule metabolic process  response to ethanol  metal ion binding  receptor antagonist activity  NAD binding  oxidation-reduction process  extracellular negative regulation of signal transduction  
Ontology : EGO-EBIretinoid metabolic process  alcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  aldehyde oxidase activity  retinol dehydrogenase activity  extracellular region  nucleolus  cytoplasm  cytosol  ethanol catabolic process  ethanol oxidation  ethanol oxidation  xenobiotic metabolic process  zinc ion binding  response to bacterium  fatty acid omega-oxidation  retinol binding  ethanol binding  retinol metabolic process  retinoic acid metabolic process  protein homodimerization activity  small molecule metabolic process  response to ethanol  metal ion binding  receptor antagonist activity  NAD binding  oxidation-reduction process  extracellular negative regulation of signal transduction  
Pathways : KEGGMetabolism of xenobiotics by cytochrome P450Glycerolipid metabolismBile acid biosynthesisGlycolysis / GluconeogenesisTyrosine metabolismFatty acid metabolism1- and 2-Methylnaphthalene degradation
Other databases
Probes
Litterature
PubMed45 Pubmed reference(s) in Entrez
PubGeneADH7
iHOPADH7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:32:07 CEST 2013
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