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ADH7 (alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide)

Identity

Other namesADH4
HGNC (Hugo) ADH7
LocusID (NCBI) 131
Location 4q23
Location_base_pair Starts at 100333418 and ends at 100356667 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ADH7   256
Cards
Entrez_Gene (NCBI)ADH7  131  alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
GeneCards (Weizmann)ADH7
Ensembl (Hinxton)ENSG00000196344 [Gene_View]  chr4:100333418-100356667 [Contig_View]  ADH7 [Vega]
ICGC DataPortalENSG00000196344
AceView (NCBI)ADH7
Genatlas (Paris)ADH7
WikiGenes131
SOURCE (Princeton)NM_000673 NM_001166504
Genomic and cartography
GoldenPath (UCSC)ADH7  -  4q23   chr4:100333418-100356667 -  4q23   [Description]    (hg19-Feb_2009)
EnsemblADH7 - 4q23 [CytoView]
Mapping of homologs : NCBIADH7 [Mapview]
OMIM600086   
Gene and transcription
Genbank (Entrez)AK223472 AK301657 AK301696 AK310811 AK312854
RefSeq transcript (Entrez)NM_000673 NM_001166504
RefSeq genomic (Entrez)AC_000136 NC_000004 NC_018915 NT_016354 NW_001838915 NW_004929320
Consensus coding sequences : CCDS (NCBI)ADH7
Cluster EST : UnigeneHs.389 [ NCBI ]
CGAP (NCI)Hs.389
Alternative Splicing : Fast-db (Paris)GSHG0023426
Alternative Splicing GalleryENSG00000196344
Gene ExpressionADH7 [ NCBI-GEO ]     ADH7 [ SEEK ]   ADH7 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP40394 (Uniprot)
NextProtP40394  [Medical]
With graphics : InterProP40394
Splice isoforms : SwissVarP40394 (Swissvar)
Catalytic activity : Enzyme1.1.1.1 [ Enzyme-Expasy ]   1.1.1.11.1.1.1 [ IntEnz-EBI ]   1.1.1.1 [ BRENDA ]   1.1.1.1 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ADH_ZINC (PS00059)   
Domains : Interpro (EBI)ADH_C    ADH_GroES-like    ADH_SF_Zn-type    ADH_Zn_CS    GroES-like    NAD(P)-bd_dom    Zinc_ADH_IV   
Related proteins : CluSTrP40394
Domain families : Pfam (Sanger)ADH_N (PF08240)    ADH_zinc_N (PF00107)   
Domain families : Pfam (NCBI)pfam08240    pfam00107   
DMDM Disease mutations131
Blocks (Seattle)P40394
PDB (SRS)1AGN    1D1S    1D1T   
PDB (PDBSum)1AGN    1D1S    1D1T   
PDB (IMB)1AGN    1D1S    1D1T   
PDB (RSDB)1AGN    1D1S    1D1T   
Human Protein AtlasENSG00000196344
Peptide AtlasP40394
HPRD02515
IPIIPI00872487   IPI00908386   IPI00945694   IPI00946812   
Protein Interaction databases
DIP (DOE-UCLA)P40394
IntAct (EBI)P40394
FunCoupENSG00000196344
BioGRIDADH7
IntegromeDBADH7
STRING (EMBL)ADH7
Ontologies - Pathways
QuickGOP40394
Ontology : AmiGOretinoid metabolic process  alcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  aldehyde oxidase activity  retinol dehydrogenase activity  extracellular region  cytosol  ethanol catabolic process  ethanol oxidation  ethanol oxidation  xenobiotic metabolic process  zinc ion binding  response to bacterium  fatty acid omega-oxidation  retinol binding  ethanol binding  retinol metabolic process  retinoic acid metabolic process  small molecule metabolic process  response to ethanol  receptor antagonist activity  oxidation-reduction process  extracellular negative regulation of signal transduction  
Ontology : EGO-EBIretinoid metabolic process  alcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  aldehyde oxidase activity  retinol dehydrogenase activity  extracellular region  cytosol  ethanol catabolic process  ethanol oxidation  ethanol oxidation  xenobiotic metabolic process  zinc ion binding  response to bacterium  fatty acid omega-oxidation  retinol binding  ethanol binding  retinol metabolic process  retinoic acid metabolic process  small molecule metabolic process  response to ethanol  receptor antagonist activity  oxidation-reduction process  extracellular negative regulation of signal transduction  
Pathways : KEGGGlycolysis / Gluconeogenesis    Fatty acid degradation    Tyrosine metabolism    Retinol metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
Protein Interaction DatabaseADH7
Wikipedia pathwaysADH7
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ADH7
SNP (GeneSNP Utah)ADH7
SNP : HGBaseADH7
Genetic variants : HAPMAPADH7
1000_GenomesADH7 
ICGC programENSG00000196344 
CONAN: Copy Number AnalysisADH7 
Somatic Mutations in Cancer : COSMICADH7 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
DECIPHER (Syndromes)4:100333418-100356667
Mutations and Diseases : HGMDADH7
OMIM600086   
MedgenADH7
GENETestsADH7
Disease Genetic AssociationADH7
Huge Navigator ADH7 [HugePedia]  ADH7 [HugeCancerGEM]
Genomic VariantsADH7  ADH7 [DGVbeta]
Exome VariantADH7
dbVarADH7
ClinVarADH7
snp3D : Map Gene to Disease131
General knowledge
Homologs : HomoloGeneADH7
Homology/Alignments : Family Browser (UCSC)ADH7
Phylogenetic Trees/Animal Genes : TreeFamADH7
Chemical/Protein Interactions : CTD131
Chemical/Pharm GKB GenePA24577
Clinical trialADH7
Cancer Resource (Charite)ENSG00000196344
Other databases
Probes
Litterature
PubMed50 Pubmed reference(s) in Entrez
CoreMineADH7
GoPubMedADH7
iHOPADH7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Nov 8 17:10:17 CET 2014

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