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ADH7 (alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide)

Identity

Other namesADH4
HGNC (Hugo) ADH7
LocusID (NCBI) 131
Atlas_Id 46969
Location 4q23
Location_base_pair Starts at 100333418 and ends at 100356667 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADH7 (4q23) / CXCR5 (11q23.3)ADH7 4q23 / CXCR5 11q23.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)ADH7   256
Cards
Entrez_Gene (NCBI)ADH7  131  alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
GeneCards (Weizmann)ADH7
Ensembl hg19 (Hinxton)ENSG00000196344 [Gene_View]  chr4:100333418-100356667 [Contig_View]  ADH7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000196344 [Gene_View]  chr4:100333418-100356667 [Contig_View]  ADH7 [Vega]
ICGC DataPortalENSG00000196344
TCGA cBioPortalADH7
AceView (NCBI)ADH7
Genatlas (Paris)ADH7
WikiGenes131
SOURCE (Princeton)ADH7
Genomic and cartography
GoldenPath hg19 (UCSC)ADH7  -     chr4:100333418-100356667 -  4q23   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)ADH7  -     4q23   [Description]    (hg38-Dec_2013)
EnsemblADH7 - 4q23 [CytoView hg19]  ADH7 - 4q23 [CytoView hg38]
Mapping of homologs : NCBIADH7 [Mapview hg19]  ADH7 [Mapview hg38]
OMIM600086   
Gene and transcription
Genbank (Entrez)AK223472 AK301657 AK301696 AK310811 AK312854
RefSeq transcript (Entrez)NM_000673 NM_001166504
RefSeq genomic (Entrez)NC_000004 NC_018915 NT_016354 NW_004929320
Consensus coding sequences : CCDS (NCBI)ADH7
Cluster EST : UnigeneHs.389 [ NCBI ]
CGAP (NCI)Hs.389
Alternative Splicing GalleryENSG00000196344
Gene ExpressionADH7 [ NCBI-GEO ]   ADH7 [ EBI - ARRAY_EXPRESS ]   ADH7 [ SEEK ]   ADH7 [ MEM ]
Gene Expression Viewer (FireBrowse)ADH7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)131
GTEX Portal (Tissue expression)ADH7
Protein : pattern, domain, 3D structure
UniProt/SwissProtP40394 (Uniprot)
NextProtP40394  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP40394
Splice isoforms : SwissVarP40394 (Swissvar)
Catalytic activity : Enzyme1.1.1.1 [ Enzyme-Expasy ]   1.1.1.11.1.1.1 [ IntEnz-EBI ]   1.1.1.1 [ BRENDA ]   1.1.1.1 [ KEGG ]   
PhosPhoSitePlusP40394
Domaine pattern : Prosite (Expaxy)ADH_ZINC (PS00059)   
Domains : Interpro (EBI)ADH_C    ADH_N    ADH_SF_Zn-type    ADH_Zn_CS    GroES-like    NAD(P)-bd_dom   
Domain families : Pfam (Sanger)ADH_N (PF08240)    ADH_zinc_N (PF00107)   
Domain families : Pfam (NCBI)pfam08240    pfam00107   
DMDM Disease mutations131
Blocks (Seattle)ADH7
PDB (SRS)1AGN    1D1S    1D1T   
PDB (PDBSum)1AGN    1D1S    1D1T   
PDB (IMB)1AGN    1D1S    1D1T   
PDB (RSDB)1AGN    1D1S    1D1T   
Structural Biology KnowledgeBase1AGN    1D1S    1D1T   
SCOP (Structural Classification of Proteins)1AGN    1D1S    1D1T   
CATH (Classification of proteins structures)1AGN    1D1S    1D1T   
SuperfamilyP40394
Human Protein AtlasENSG00000196344
Peptide AtlasP40394
HPRD02515
IPIIPI00872487   IPI00908386   IPI00945694   IPI00946812   
Protein Interaction databases
DIP (DOE-UCLA)P40394
IntAct (EBI)P40394
FunCoupENSG00000196344
BioGRIDADH7
STRING (EMBL)ADH7
ZODIACADH7
Ontologies - Pathways
QuickGOP40394
Ontology : AmiGOretinoid metabolic process  alcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  alcohol dehydrogenase activity, zinc-dependent  aldehyde oxidase activity  retinol dehydrogenase activity  extracellular region  cytosol  ethanol catabolic process  ethanol oxidation  ethanol oxidation  zinc ion binding  response to bacterium  fatty acid omega-oxidation  retinol binding  ethanol binding  retinol metabolic process  retinoic acid metabolic process  response to ethanol  receptor antagonist activity  oxidation-reduction process  extracellular negative regulation of signal transduction  
Ontology : EGO-EBIretinoid metabolic process  alcohol dehydrogenase (NAD) activity  alcohol dehydrogenase activity, zinc-dependent  alcohol dehydrogenase activity, zinc-dependent  aldehyde oxidase activity  retinol dehydrogenase activity  extracellular region  cytosol  ethanol catabolic process  ethanol oxidation  ethanol oxidation  zinc ion binding  response to bacterium  fatty acid omega-oxidation  retinol binding  ethanol binding  retinol metabolic process  retinoic acid metabolic process  response to ethanol  receptor antagonist activity  oxidation-reduction process  extracellular negative regulation of signal transduction  
Pathways : KEGGGlycolysis / Gluconeogenesis    Fatty acid degradation    Tyrosine metabolism    Retinol metabolism    Metabolism of xenobiotics by cytochrome P450    Drug metabolism - cytochrome P450    Chemical carcinogenesis   
NDEx Network
Atlas of Cancer Signalling NetworkADH7
Wikipedia pathwaysADH7
Orthology - Evolution
OrthoDB131
GeneTree (enSembl)ENSG00000196344
Phylogenetic Trees/Animal Genes : TreeFamADH7
Homologs : HomoloGeneADH7
Homology/Alignments : Family Browser (UCSC)ADH7
Gene fusions - Rearrangements
Fusion: TCGAADH7 4q23 CXCR5 11q23.3 HNSC
Polymorphisms : SNP, variants
NCBI Variation ViewerADH7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)ADH7
dbVarADH7
ClinVarADH7
1000_GenomesADH7 
Exome Variant ServerADH7
ExAC (Exome Aggregation Consortium)ADH7 (select the gene name)
Genetic variants : HAPMAP131
Genomic Variants (DGV)ADH7 [DGVbeta]
Mutations
ICGC Data PortalADH7 
TCGA Data PortalADH7 
Broad Tumor PortalADH7
OASIS PortalADH7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICADH7 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch ADH7
DgiDB (Drug Gene Interaction Database)ADH7
DoCM (Curated mutations)ADH7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)ADH7 (select a term)
intoGenADH7
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)4:100333418-100356667  ENSG00000196344
CONAN: Copy Number AnalysisADH7 
Mutations and Diseases : HGMDADH7
OMIM600086   
MedgenADH7
Genetic Testing Registry ADH7
NextProtP40394 [Medical]
TSGene131
GENETestsADH7
Huge Navigator ADH7 [HugePedia]
snp3D : Map Gene to Disease131
BioCentury BCIQADH7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD131
Chemical/Pharm GKB GenePA24577
Clinical trialADH7
Miscellaneous
canSAR (ICR)ADH7 (select the gene name)
Probes
Litterature
PubMed54 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineADH7
EVEXADH7
GoPubMedADH7
iHOPADH7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 8 18:36:11 CEST 2016

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