ADI1 (acireductone dioxygenase 1)

2007-02-01  

Identity

HGNC
LOCATION
2p25.3
LOCUSID
ALIAS
APL1,ARD,Fe-ARD,HMFT1638,MTCBP1,Ni-ARD,SIPL,mtnD
FUSION GENES

Other Information

Locus ID:

NCBI: 55256
MIM: 613400
HGNC: 30576
Ensembl: ENSG00000182551

Variants:

dbSNP: 55256
ClinVar: 55256
TCGA: ENSG00000182551
COSMIC: ADI1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000182551ENST00000327435Q9BV57
ENSG00000182551ENST00000382093Q9BV57
ENSG00000182551ENST00000415131H7C382

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
Cysteine and methionine metabolismKEGGko00270
Cysteine and methionine metabolismKEGGhsa00270
Metabolic pathwaysKEGGhsa01100
Methionine salvage pathwayKEGGhsa_M00034
Methionine salvage pathwayKEGGM00034
MetabolismREACTOMER-HSA-1430728
Metabolism of amino acids and derivativesREACTOMER-HSA-71291
Metabolism of polyaminesREACTOMER-HSA-351202
Methionine salvage pathwayREACTOMER-HSA-1237112
Sulfur amino acid metabolismREACTOMER-HSA-1614635

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
147185442004Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein-1 is a new member of the Cupin superfamily. A possible multifunctional protein acting as an invasion suppressor down-regulated in tumors.21
177861832007Expression and function of the human androgen-responsive gene ADI1 in prostate cancer.19
172126582007Regulated nucleo-cytoplasmic shuttling of human aci-reductone dioxygenase (hADI1) and its potential role in mRNA processing.7
304871812019Pancreatic tumor cell metastasis is restricted by MT1-MMP binding protein MTCBP-1.6
196266142009293 cells over-expressing human ADI1 and CD81 are permissive for serum-derived hepatitis C virus infection.5
256409482016Evidence of MTCBP-1 interaction with the cytoplasmic domain of MT1-MMP: Implications in the autophagy cell index of high-grade glioblastoma.5
265370612016Interaction between hepatic membrane type 1 matrix metalloproteinase and acireductone dioxygenase 1 regulates hepatitis C virus infection.5
280626482017Dual chemistry catalyzed by human acireductone dioxygenase.2
300669002018Enolase-phosphatase 1 as a novel potential malignant glioma indicator promotes cell proliferation and migration.2

Citation

Dessen P

ADI1 (acireductone dioxygenase 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45729/adi1