Identity
HGNC
LOCATION
1p34.3
LOCUSID
ALIAS
EIF2C,EIF2C1,GERP95,Q99,hAgo1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 26523
MIM: 606228
HGNC: 3262
Ensembl: ENSG00000092847
Variants:
dbSNP: 26523
ClinVar: 26523
TCGA: ENSG00000092847
COSMIC: AGO1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000092847 | ENST00000373204 | Q9UL18 |
| ENSG00000092847 | ENST00000373206 | Q5TA58 |
| ENSG00000092847 | ENST00000635259 | A0A0U1RQZ8 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36990227 | 2023 | LINC01116 modulates EMT process via binding with AGO1 mRNA in oesophageal squamous cell carcinoma. | 0 |
| 36990227 | 2023 | LINC01116 modulates EMT process via binding with AGO1 mRNA in oesophageal squamous cell carcinoma. | 0 |
| 34930816 | 2022 | De novo coding variants in the AGO1 gene cause a neurodevelopmental disorder with intellectual disability. | 6 |
| 35060114 | 2022 | De novo variants in AGO1 recapitulate a heterogeneous neurodevelopmental disorder phenotype. | 1 |
| 36142498 | 2022 | Association of Polymorphic Variants in Argonaute Genes with Depression Risk in a Polish Population. | 2 |
| 34930816 | 2022 | De novo coding variants in the AGO1 gene cause a neurodevelopmental disorder with intellectual disability. | 6 |
| 35060114 | 2022 | De novo variants in AGO1 recapitulate a heterogeneous neurodevelopmental disorder phenotype. | 1 |
| 36142498 | 2022 | Association of Polymorphic Variants in Argonaute Genes with Depression Risk in a Polish Population. | 2 |
| 32752954 | 2021 | Molecular crowding and conserved interface interactions of human argonaute protein-miRNA-target mRNA complex. | 1 |
| 33327713 | 2021 | Mixed-lineage leukemia protein modulates the loading of let-7a onto AGO1 by recruiting RAN. | 0 |
| 33600493 | 2021 | RanBP2/Nup358 enhances miRNA activity by sumoylating Argonautes. | 12 |
| 33832481 | 2021 | POU2F2 promotes the proliferation and motility of lung cancer cells by activating AGO1. | 6 |
| 34288373 | 2021 | LncRNA PVT1 promotes the progression of ovarian cancer by activating TGF-β pathway via miR-148a-3p/AGO1 axis. | 9 |
| 32752954 | 2021 | Molecular crowding and conserved interface interactions of human argonaute protein-miRNA-target mRNA complex. | 1 |
| 33327713 | 2021 | Mixed-lineage leukemia protein modulates the loading of let-7a onto AGO1 by recruiting RAN. | 0 |
Citation
Dessen P
AGO1 (argonaute RISC component 1)
Atlas Genet Cytogenet Oncol Haematol. 2010-03-01
Online version: http://atlasgeneticsoncology.org/gene/52819/ago1
