AGPAT5 (1-acylglycerol-3-phosphate O-acyltransferase 5)

2012-11-01  

Identity

HGNC
LOCATION
8p23.1
LOCUSID
ALIAS
1AGPAT5,LPAATE
FUSION GENES

Other Information

Locus ID:

NCBI: 55326
MIM: 614796
HGNC: 20886
Ensembl: ENSG00000155189

Variants:

dbSNP: 55326
ClinVar: 55326
TCGA: ENSG00000155189
COSMIC: AGPAT5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000155189ENST00000285518Q9NUQ2
ENSG00000155189ENST00000285518A0A024R640
ENSG00000155189ENST00000518327H0YC22
ENSG00000155189ENST00000523234E5RH21
ENSG00000155189ENST00000523586H0YAW1

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90

Pathways

PathwaySourceExternal ID
Glycerolipid metabolismKEGGko00561
Glycerophospholipid metabolismKEGGko00564
Glycerolipid metabolismKEGGhsa00561
Glycerophospholipid metabolismKEGGhsa00564
Metabolic pathwaysKEGGhsa01100
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Triglyceride BiosynthesisREACTOMER-HSA-75109
Phospholipid metabolismREACTOMER-HSA-1483257
Glycerophospholipid biosynthesisREACTOMER-HSA-1483206
Synthesis of PAREACTOMER-HSA-1483166
Phospholipase D signaling pathwayKEGGko04072
Phospholipase D signaling pathwayKEGGhsa04072

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
153671022005Cloning and characterization of murine 1-acyl-sn-glycerol 3-phosphate acyltransferases and their regulation by PPARalpha in murine heart.40
211731902011Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria.21
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17

Citation

Dessen P

AGPAT5 (1-acylglycerol-3-phosphate O-acyltransferase 5)

Atlas Genet Cytogenet Oncol Haematol. 2012-11-01

Online version: http://atlasgeneticsoncology.org/gene/52967/agpat5