Identity
HGNC
LOCATION
3q24
LOCUSID
ALIAS
AG2S,AGTR1B,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,HAT1R
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 185
MIM: 106165
HGNC: 336
Ensembl: ENSG00000144891
Variants:
dbSNP: 185
ClinVar: 185
TCGA: ENSG00000144891
COSMIC: AGTR1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA146096020 | nitrendipine | Chemical | ClinicalAnnotation | associated | PD | 8952600 | |
| PA164712308 | Ace Inhibitors, Plain | Chemical | ClinicalAnnotation | associated | PD | 18347611, 23407050 | |
| PA164713347 | Thiazides, plain | Chemical | ClinicalAnnotation | associated | PD | 19247266 | |
| PA166109554 | angiotensin II | Chemical | ClinicalAnnotation | associated | PD | 10594793 | |
| PA443796 | Coronary Artery Disease | Disease | ClinicalAnnotation | associated | PD | 20712529, 23407050 | |
| PA443890 | Diabetes Mellitus, Type 2 | Disease | ClinicalAnnotation | associated | PD | 19286758 | |
| PA444370 | Heart Failure | Disease | ClinicalAnnotation | associated | PD | 18594050 | |
| PA444552 | Hypertension | Disease | ClinicalAnnotation | associated | PD | 18347611, 8952600 | |
| PA444797 | Liver Cirrhosis | Disease | ClinicalAnnotation | associated | PD | 15743363 | |
| PA448500 | atorvastatin | Chemical | ClinicalAnnotation | associated | PK | ||
| PA448765 | candesartan | Chemical | ClinicalAnnotation | associated | PD | 18594050 | |
| PA448780 | captopril | Chemical | ClinicalAnnotation | associated | PD | 19286758 | |
| PA450268 | losartan | Chemical | ClinicalAnnotation, Pathway | associated | PD | 10594793, 15743363, 20436376 | |
| PA450877 | perindopril | Chemical | ClinicalAnnotation | associated | PD | 20712529, 8952600 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38061417 | 2024 | Regulation of vascular angiotensin II type 1 and type 2 receptor and angiotensin-(1-7)/MasR signaling in normal and hypertensive pregnancy. | 3 |
| 38262555 | 2024 | Evidence for heterodimerization and functional interaction of the urotensin II and the angiotensin II type 1 receptors. | 0 |
| 38285770 | 2024 | Investigating the association of Angiotensin II Type I Receptor A1166C Polymorphism with Breast Cancer Risk in the Pakistani Population. | 0 |
| 38380450 | 2024 | Genetic Variations of Angiotensinogen, Angiotensin Converting Enzyme, and Angiotensin Type 1 Receptor with the Risk of Pulmonary Tuberculosis. | 0 |
| 38635772 | 2024 | Effect of AGTR1 A1166C genetic polymorphism on coronary artery lesions and mortality in patients with acute myocardial infarction. | 0 |
| 38649831 | 2024 | A loss-of-function AGTR1 variant in a critically-ill infant with renal tubular dysgenesis: case presentation and literature review. | 0 |
| 38852191 | 2024 | Significant Association of Candidate Genes (AGTR1 and TGF-Β1) Polymorphism with Diabetic Nephropathy in Diabetes Mellitus Type 2 Patients. | 0 |
| 38061417 | 2024 | Regulation of vascular angiotensin II type 1 and type 2 receptor and angiotensin-(1-7)/MasR signaling in normal and hypertensive pregnancy. | 3 |
| 38262555 | 2024 | Evidence for heterodimerization and functional interaction of the urotensin II and the angiotensin II type 1 receptors. | 0 |
| 38285770 | 2024 | Investigating the association of Angiotensin II Type I Receptor A1166C Polymorphism with Breast Cancer Risk in the Pakistani Population. | 0 |
| 38380450 | 2024 | Genetic Variations of Angiotensinogen, Angiotensin Converting Enzyme, and Angiotensin Type 1 Receptor with the Risk of Pulmonary Tuberculosis. | 0 |
| 38635772 | 2024 | Effect of AGTR1 A1166C genetic polymorphism on coronary artery lesions and mortality in patients with acute myocardial infarction. | 0 |
| 38649831 | 2024 | A loss-of-function AGTR1 variant in a critically-ill infant with renal tubular dysgenesis: case presentation and literature review. | 0 |
| 38852191 | 2024 | Significant Association of Candidate Genes (AGTR1 and TGF-Β1) Polymorphism with Diabetic Nephropathy in Diabetes Mellitus Type 2 Patients. | 0 |
| 34860335 | 2023 | Candidate Gene of NOS3, MMP3, AGT, and AGT1R and Pathway Analyses for Platelet Reactivity and Clinical Outcomes of Repeat Revascularization After First PCI in Chinese Patients. | 0 |
Citation
Dessen P
AGTR1 (angiotensin II receptor type 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/46595/agtr1
