Atlas of Genetics and Cytogenetics in Oncology and Haematology

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AHCTF1 (AT-hook containing transcription factor 1)

Identity

Alias_namesAT hook containing transcription factor 1
Alias_symbol (synonym)ELYS
Other aliasMST108
MSTP108
TMBS62
HGNC (Hugo) AHCTF1
LocusID (NCBI) 25909
Atlas_Id 54112
Location 1q44  [Link to chromosome band 1q44]
Location_base_pair Starts at 246839098 and ends at 246931424 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
AHCTF1 (1q44) / GIGYF2 (2q37.1)AHCTF1 (1q44) / NAAA (4q21.1)FBP1 (9q22.32) / AHCTF1 (1q44)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(1;4)(q44;q21) AHCTF1/NAAA

External links

Nomenclature
HGNC (Hugo)AHCTF1   24618
Cards
Entrez_Gene (NCBI)AHCTF1  25909  AT-hook containing transcription factor 1
AliasesELYS; MST108; MSTP108; TMBS62
GeneCards (Weizmann)AHCTF1
Ensembl hg19 (Hinxton)ENSG00000153207 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000153207 [Gene_View]  ENSG00000153207 [Sequence]  chr1:246839098-246931424 [Contig_View]  AHCTF1 [Vega]
ICGC DataPortalENSG00000153207
TCGA cBioPortalAHCTF1
AceView (NCBI)AHCTF1
Genatlas (Paris)AHCTF1
WikiGenes25909
SOURCE (Princeton)AHCTF1
Genetics Home Reference (NIH)AHCTF1
Genomic and cartography
GoldenPath hg38 (UCSC)AHCTF1  -     chr1:246839098-246931424 -  1q44   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)AHCTF1  -     1q44   [Description]    (hg19-Feb_2009)
GoldenPathAHCTF1 - 1q44 [CytoView hg19]  AHCTF1 - 1q44 [CytoView hg38]
ImmunoBaseENSG00000153207
Mapping of homologs : NCBIAHCTF1 [Mapview hg19]  AHCTF1 [Mapview hg38]
OMIM610853   
Gene and transcription
Genbank (Entrez)AB059277 AF173978 AK091364 AK091510 AK095398
RefSeq transcript (Entrez)NM_001323342 NM_001323343 NM_015446 NM_175865
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)AHCTF1
Cluster EST : UnigeneHs.300887 [ NCBI ]
CGAP (NCI)Hs.300887
Alternative Splicing GalleryENSG00000153207
Gene ExpressionAHCTF1 [ NCBI-GEO ]   AHCTF1 [ EBI - ARRAY_EXPRESS ]   AHCTF1 [ SEEK ]   AHCTF1 [ MEM ]
Gene Expression Viewer (FireBrowse)AHCTF1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25909
GTEX Portal (Tissue expression)AHCTF1
Human Protein AtlasENSG00000153207-AHCTF1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WYP5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WYP5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WYP5
Splice isoforms : SwissVarQ8WYP5
PhosPhoSitePlusQ8WYP5
Domains : Interpro (EBI)ELYS-bb    ELYS_dom    Quinoprotein_ADH-like_supfam   
Domain families : Pfam (Sanger)ELYS (PF13934)    ELYS-bb (PF16687)   
Domain families : Pfam (NCBI)pfam13934    pfam16687   
Conserved Domain (NCBI)AHCTF1
DMDM Disease mutations25909
Blocks (Seattle)AHCTF1
SuperfamilyQ8WYP5
Human Protein Atlas [tissue]ENSG00000153207-AHCTF1 [tissue]
Peptide AtlasQ8WYP5
HPRD09935
IPIIPI00954159   IPI00979341   IPI00979064   IPI00947495   
Protein Interaction databases
DIP (DOE-UCLA)Q8WYP5
IntAct (EBI)Q8WYP5
FunCoupENSG00000153207
BioGRIDAHCTF1
STRING (EMBL)AHCTF1
ZODIACAHCTF1
Ontologies - Pathways
QuickGOQ8WYP5
Ontology : AmiGOcondensed chromosome kinetochore  chromatin  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  nucleus  nuclear pore  nucleoplasm  cytosol  regulation of transcription by RNA polymerase II  cell cycle  protein transport  nuclear matrix  nuclear pore outer ring  nuclear membrane  regulation of cytokinesis  mRNA transport  nuclear pore complex assembly  cell division  extracellular exosome  
Ontology : EGO-EBIcondensed chromosome kinetochore  chromatin  DNA-binding transcription factor activity, RNA polymerase II-specific  DNA binding  nucleus  nuclear pore  nucleoplasm  cytosol  regulation of transcription by RNA polymerase II  cell cycle  protein transport  nuclear matrix  nuclear pore outer ring  nuclear membrane  regulation of cytokinesis  mRNA transport  nuclear pore complex assembly  cell division  extracellular exosome  
NDEx NetworkAHCTF1
Atlas of Cancer Signalling NetworkAHCTF1
Wikipedia pathwaysAHCTF1
Orthology - Evolution
OrthoDB25909
GeneTree (enSembl)ENSG00000153207
Phylogenetic Trees/Animal Genes : TreeFamAHCTF1
HOGENOMQ8WYP5
Homologs : HomoloGeneAHCTF1
Homology/Alignments : Family Browser (UCSC)AHCTF1
Gene fusions - Rearrangements
Fusion : MitelmanAHCTF1/NAAA [1q44/4q21.1]  
Fusion : QuiverAHCTF1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerAHCTF1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)AHCTF1
dbVarAHCTF1
ClinVarAHCTF1
1000_GenomesAHCTF1 
Exome Variant ServerAHCTF1
ExAC (Exome Aggregation Consortium)ENSG00000153207
GNOMAD BrowserENSG00000153207
Varsome BrowserAHCTF1
Genetic variants : HAPMAP25909
Genomic Variants (DGV)AHCTF1 [DGVbeta]
DECIPHERAHCTF1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisAHCTF1 
Mutations
ICGC Data PortalAHCTF1 
TCGA Data PortalAHCTF1 
Broad Tumor PortalAHCTF1
OASIS PortalAHCTF1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICAHCTF1  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DAHCTF1
Mutations and Diseases : HGMDAHCTF1
intOGen PortalAHCTF1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch AHCTF1
DgiDB (Drug Gene Interaction Database)AHCTF1
DoCM (Curated mutations)AHCTF1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)AHCTF1 (select a term)
intoGenAHCTF1
Cancer3DAHCTF1(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610853   
Orphanet
DisGeNETAHCTF1
MedgenAHCTF1
Genetic Testing Registry AHCTF1
NextProtQ8WYP5 [Medical]
TSGene25909
GENETestsAHCTF1
Target ValidationAHCTF1
Huge Navigator AHCTF1 [HugePedia]
snp3D : Map Gene to Disease25909
BioCentury BCIQAHCTF1
ClinGenAHCTF1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25909
Chemical/Pharm GKB GenePA142672631
Clinical trialAHCTF1
Miscellaneous
canSAR (ICR)AHCTF1 (select the gene name)
DataMed IndexAHCTF1
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineAHCTF1
EVEXAHCTF1
GoPubMedAHCTF1
iHOPAHCTF1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Nov 13 17:31:37 CET 2019
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