AIFM3 (apoptosis inducing factor mitochondria associated 3)

2007-02-01  

Identity

HGNC
AIFM3
LOCATION
22q11.21
LOCUSID
150209
ALIAS
AIFL

Other Information

Locus ID:

NCBI: 150209
MIM: 617298
HGNC: 26398
Ensembl: ENSG00000183773

Variants:

dbSNP: 150209
ClinVar: 150209
TCGA: ENSG00000183773
COSMIC: AIFM3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183773ENST00000399163Q96NN9
ENSG00000183773ENST00000399167Q96NN9
ENSG00000183773ENST00000405089Q96NN9
ENSG00000183773ENST00000417515F8WFB6
ENSG00000183773ENST00000426113F8WC30
ENSG00000183773ENST00000434714C9K029
ENSG00000183773ENST00000440238Q96NN9
ENSG00000183773ENST00000441376C9JPU8

Expression (GTEx)

0
10
20
30
40
50
60
70
80
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
223879012012Downregulation of miR-210 expression inhibits proliferation, induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro.52
160010802005AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells.35
157646042005Molecular cloning and characterization of a human AIF-like gene with ability to induce apoptosis.20
208776242010Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.17
191664162008H. pylori-induced apoptosis in human gastric cancer cells mediated via the release of apoptosis-inducing factor from mitochondria.16
274730832016High expression of apoptosis-inducing factor, mitochondrion-associated 3 (AIFM3) in human cholangiocarcinoma.4
310884222019Clinical implications of a novel prognostic factor AIFM3 in breast cancer patients.3
225508672011[Expression of AIF and CGRP markers in pineal gland and thymus during aging].0

Citation

Dessen P

AIFM3 (apoptosis inducing factor mitochondria associated 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45652/aifm3