Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 204
MIM: 103020
HGNC: 362
Ensembl: ENSG00000004455
Variants:
dbSNP: 204
ClinVar: 204
TCGA: ENSG00000004455
COSMIC: AK2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA10005 | adefovir dipivoxil | Chemical | Pathway | associated | |||
| PA10204 | tenofovir | Chemical | Pathway | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37161605 | 2023 | Adenylate kinase 2 is a biomarker related to the prognosis of glioma and the immune microenvironment. | 2 |
| 37527777 | 2023 | Colorectal cancer-associated mutations impair EphB1 kinase function. | 3 |
| 37161605 | 2023 | Adenylate kinase 2 is a biomarker related to the prognosis of glioma and the immune microenvironment. | 2 |
| 37527777 | 2023 | Colorectal cancer-associated mutations impair EphB1 kinase function. | 3 |
| 35585049 | 2022 | AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis. | 1 |
| 35585049 | 2022 | AK2 is an AMP-sensing negative regulator of BRAF in tumorigenesis. | 1 |
| 33560378 | 2021 | Adenylate kinase 2 expression and addiction in T-ALL. | 6 |
| 33560378 | 2021 | Adenylate kinase 2 expression and addiction in T-ALL. | 6 |
| 31862378 | 2020 | Hypomorphic variants in AK2 reveal the contribution of mitochondrial function to B-cell activation. | 6 |
| 32532877 | 2020 | Reticular dysgenesis caused by an intronic pathogenic variant in AK2. | 2 |
| 31862378 | 2020 | Hypomorphic variants in AK2 reveal the contribution of mitochondrial function to B-cell activation. | 6 |
| 32532877 | 2020 | Reticular dysgenesis caused by an intronic pathogenic variant in AK2. | 2 |
| 31247120 | 2019 | Genome-Wide Analysis of DNA Methylation and Antituberculosis Drug-Induced Liver Injury in the Han Chinese Population. | 11 |
| 31780678 | 2019 | Prognostic and therapeutic potential of Adenylate kinase 2 in lung adenocarcinoma. | 19 |
| 31247120 | 2019 | Genome-Wide Analysis of DNA Methylation and Antituberculosis Drug-Induced Liver Injury in the Han Chinese Population. | 11 |
Citation
Dessen P
AK2 (adenylate kinase 2)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/606/ak2
