AKAP3 (A-kinase anchoring protein 3)

2007-02-01  

Identity

HGNC
LOCATION
12p13.32
LOCUSID
ALIAS
AKAP
FUSION GENES

Other Information

Locus ID:

NCBI: 10566
MIM: 604689
HGNC: 373
Ensembl: ENSG00000111254

Variants:

dbSNP: 10566
ClinVar: 10566
TCGA: ENSG00000111254
COSMIC: AKAP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111254ENST00000228850O75969
ENSG00000111254ENST00000228850V9HWD4
ENSG00000111254ENST00000536414F5H2S4
ENSG00000111254ENST00000540967F5H7P4
ENSG00000111254ENST00000545990O75969
ENSG00000111254ENST00000545990V9HWD4

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
125094402003Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein/p97 during capacitation.77
176830362007Human spermatozoa contain multiple targets for protein S-nitrosylation: an alternative mechanism of the modulation of sperm function by nitric oxide?43
160059462005A-kinase anchoring protein 3 messenger RNA expression correlates with poor prognosis in epithelial ovarian cancer.10
212402912011CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath.9
229415072012Identification of the cancer/testis antigens AKAP3 and CTp11 by SEREX in hepatocellular carcinoma.7
146186202004A-kinase anchoring protein 3 messenger RNA expression in ovarian cancer and its implication on prognosis.6
264585422015AKAP3 correlates with triple negative status and disease free survival in breast cancer.1
312541432019Human OVGP1 enhances tyrosine phosphorylation of proteins in the fibrous sheath involving AKAP3 and increases sperm-zona binding.1

Citation

Dessen P

AKAP3 (A-kinase anchoring protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45668/akap3