AKAP3 (A-kinase anchoring protein 3)

2007-02-01  

Identity

HGNC
LOCATION
12p13.32
LOCUSID
ALIAS
AKAP
FUSION GENES

Other Information

Locus ID:

NCBI: 10566
MIM: 604689
HGNC: 373
Ensembl: ENSG00000111254

Variants:

dbSNP: 10566
ClinVar: 10566
TCGA: ENSG00000111254
COSMIC: AKAP3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000111254ENST00000228850O75969
ENSG00000111254ENST00000228850V9HWD4
ENSG00000111254ENST00000536414F5H2S4
ENSG00000111254ENST00000540967F5H7P4
ENSG00000111254ENST00000545990O75969
ENSG00000111254ENST00000545990V9HWD4

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
352283002023Homozygous variants in AKAP3 induce asthenoteratozoospermia and male infertility.4
352283002023Homozygous variants in AKAP3 induce asthenoteratozoospermia and male infertility.4
352566412022Structural modeling of human AKAP3 protein and in silico analysis of single nucleotide polymorphisms associated with sperm motility.3
353227482022The cancer-testis antigen a-kinase anchor protein 3 facilitates breast cancer progression via activation of the PTEN/PI3K/AKT/mTOR signaling.3
352566412022Structural modeling of human AKAP3 protein and in silico analysis of single nucleotide polymorphisms associated with sperm motility.3
353227482022The cancer-testis antigen a-kinase anchor protein 3 facilitates breast cancer progression via activation of the PTEN/PI3K/AKT/mTOR signaling.3
349440092021Protein Kinase A (PRKA) Activity Is Regulated by the Proteasome at the Onset of Human Sperm Capacitation.5
349440092021Protein Kinase A (PRKA) Activity Is Regulated by the Proteasome at the Onset of Human Sperm Capacitation.5
312541432019Human OVGP1 enhances tyrosine phosphorylation of proteins in the fibrous sheath involving AKAP3 and increases sperm-zona binding.12
312541432019Human OVGP1 enhances tyrosine phosphorylation of proteins in the fibrous sheath involving AKAP3 and increases sperm-zona binding.12
264585422015AKAP3 correlates with triple negative status and disease free survival in breast cancer.5
264585422015AKAP3 correlates with triple negative status and disease free survival in breast cancer.5
229415072012Identification of the cancer/testis antigens AKAP3 and CTp11 by SEREX in hepatocellular carcinoma.12
229415072012Identification of the cancer/testis antigens AKAP3 and CTp11 by SEREX in hepatocellular carcinoma.12
212402912011CABYR binds to AKAP3 and Ropporin in the human sperm fibrous sheath.17

Citation

Dessen P

AKAP3 (A-kinase anchoring protein 3)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/45668/akap3