AKR7A3 (aldo-keto reductase family 7 member A3)

2003-05-01 Affiliation

Identity

HGNC

AKR7A3

LOCATION

1p36.13

LOCUSID

22977

ALIAS

AFAR2

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 22977
MIM: 608477
HGNC: 390
Ensembl: ENSG00000162482

Variants:

dbSNP: 22977
ClinVar: 22977
TCGA: ENSG00000162482
COSMIC: AKR7A3

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000162482	ENST00000361640	O95154
ENSG00000162482	ENST00000361640	A0A384MDN8

Expression (GTEx)

100

150

200

250

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism of xenobiotics by cytochrome P450	KEGG	ko00980
Metabolism of xenobiotics by cytochrome P450	KEGG	hsa00980
Metabolism	REACTOME	R-HSA-1430728
Biological oxidations	REACTOME	R-HSA-211859
Aflatoxin activation and detoxification	REACTOME	R-HSA-5423646

References

Pubmed ID	Year	Title	Citations
20453000	2010	A Large-scale genetic association study of esophageal adenocarcinoma risk.	23
29383608	2018	Aldo-Keto Reductases as Early Biomarkers of Hepatocellular Carcinoma: A Comparison Between Animal Models and Human HCC.	6

Citation

Dessen P

AKR7A3 (aldo-keto reductase family 7 member A3)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/614/akr7a3