ALKAL2 (ALK and LTK ligand 2)

2017-04-01 Affiliation

Identity

HGNC

ALKAL2

LOCATION

2p25.3

LOCUSID

285016

ALIAS

AUGA,FAM150B,PRO1097,RGPG542

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 285016
HGNC: 27683
Ensembl: ENSG00000189292

Variants:

dbSNP: 285016
ClinVar: 285016
TCGA: ENSG00000189292
COSMIC: ALKAL2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000189292	ENST00000344414	B5MC33
ENSG00000189292	ENST00000401489	H0Y3U4
ENSG00000189292	ENST00000401503	B5MCG6
ENSG00000189292	ENST00000403610	Q6UX46
ENSG00000189292	ENST00000405290	B5MC33
ENSG00000189292	ENST00000452023	A0A0B4J1W8
ENSG00000189292	ENST00000619265	Q6UX46

Expression (GTEx)

100

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

References

Pubmed ID	Year	Title	Citations
26418745	2015	FAM150A and FAM150B are activating ligands for anaplastic lymphoma kinase.	40
26630010	2015	Augmentor α and β (FAM150) are ligands of the receptor tyrosine kinases ALK and LTK: Hierarchy and specificity of ligand-receptor interactions.	39
25331893	2014	Deorphanization of the human leukocyte tyrosine kinase (LTK) receptor by a signaling screen of the extracellular proteome.	18
29317532	2018	ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells.	15

Citation

Dessen P

ALKAL2 (ALK and LTK ligand 2)

Atlas Genet Cytogenet Oncol Haematol. 2017-04-01

Online version: http://atlasgeneticsoncology.org/gene/56753/alkal2