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ALKBH1 (alkB, alkylation repair homolog 1 (E. coli))

Identity

Other namesABH
ABH1
ALKBH
alkB
hABH
HGNC (Hugo) ALKBH1
LocusID (NCBI) 8846
Location 14q24.3
Location_base_pair Starts at 78138749 and ends at 78174356 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ALKBH1   17911
Entrez_Gene (NCBI)ALKBH1  8846  alkB, alkylation repair homolog 1 (E. coli)
Cards
GeneCards (Weizmann)ALKBH1
Ensembl (Hinxton)ENSG00000100601 [Gene_View]  chr14:78138749-78174356 [Contig_View]  ALKBH1 [Vega]
AceView (NCBI)ALKBH1
Genatlas (Paris)ALKBH1
SOURCE (Stanford)NM_001039506 NM_006020
Genomic and cartography
GoldenPath (UCSC)ALKBH1  -  14q24.3   chr14:78138749-78174356 -  14q24.3   [Description]    (hg19-Feb_2009)
EnsemblALKBH1 - 14q24.3 [CytoView]
Mapping of homologs : NCBIALKBH1 [Mapview]
OMIM605345   
Gene and transcription
Genbank (Entrez)BC015024 BC025787 BX537699 DQ890543 DQ893703
RefSeq transcript (SRS)NM_001039506 NM_006020
RefSeq transcript (Entrez)NM_001039506 NM_006020
RefSeq genomic (SRS)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838113 NW_004078079
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838113 NW_004078079
Consensus coding sequences : CCDS (NCBI)ALKBH1
Cluster EST : UnigeneHs.94542 [ SRS ] Hs.94542 [ NCBI ]
CGAP (NCI)Hs.94542
Alternative Splicing : Fast-db (Paris)GSHG0009522
Alternative Splicing GalleryENSG00000100601
Gene ExpressionALKBH1 [ NCBI-GEO ]   ALKBH1 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13686 (SRS) Q13686 (Uniprot)
NextProtQ13686
With graphics : InterProQ13686
Splice isoforms : SwissVarQ13686(Swissvar)
Domaine pattern : Prosite (SRS)FE2OG_OXY (PS51471)   
Domaine pattern : Prosite (Expaxy)FE2OG_OXY (PS51471)   
Domains : Interpro (SRS)Alkb    Oxoglu/Fe-dep_dioxygenase   
Domains : Interpro (EBI)Alkb    Oxoglu/Fe-dep_dioxygenase   
Related proteins : CluSTrQ13686
Domain families : Pfam (SRS)2OG-FeII_Oxy_2 (PF13532)   
Domain families : Pfam (Sanger)2OG-FeII_Oxy_2 (PF13532)   
Domain families : Pfam (NCBI)pfam13532   
DMDM8846
Blocks (Seattle)Q13686
Human Protein AtlasENSG00000100601
IPIIPI00014482   IPI01025939   IPI01026048   
Protein Interaction databases
DIP (DOE-UCLA)Q13686
IntAct (EBI)Q13686
FunCoupENSG00000100601
REACTOMEALKBH1
Protein Interaction Database8846
BioGRIDALKBH1
InParanoidQ13686
Interologous Interaction database Q13686
IntegromeDBALKBH1
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ALKBH1
SNP (GeneSNP Utah)ALKBH1
SNP : HGBaseALKBH1
Genetic variants : HAPMAPALKBH1
Somatic Mutations in Cancer : COSMICALKBH1 
CONAN: Copy Number AnalysisALKBH1 
Mutations and Diseases : HGMDALKBH1
OMIM605345   
GENETests605345   
Disease Genetic AssociationALKBH1
Huge Navigator ALKBH1 [HugePedia]  ALKBH1 [HugeCancerGEM]
Genomic VariantsALKBH1  ALKBH1 [DGVbeta]
snp3D : Map Gene to Disease8846
General knowledge
Homologs : HomoloGeneALKBH1
Homology/Alignments : Family Browser (UCSC)ALKBH1
Phylogenetic Trees/Animal Genes : TreeFamALKBH1
Catalytic activity : Enzyme1.14.11.33 [ Enzyme-Expasy ]   1.14.11.33 [ Enzyme-SRS ]   1.14.11.33 [ IntEnz-EBI ]   1.14.11.33 [ BRENDA ]   1.14.11.33 [ KEGG ]   
Chemical/Protein Interactions : CTD8846
Chemical/Pharm GKB GenePA134906996
Clinical trialALKBH1
Cancer Resource (Charite)ENSG00000100601
Ontology : AmiGOin utero embryonic development  neuron migration  placenta development  DNA-(apurinic or apyrimidinic site) lyase activity  nuclear euchromatin  mitochondrion  DNA repair  DNA dealkylation involved in DNA repair  ferrous iron binding  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen  neuron projection development  chemoattractant activity  RNA repair  developmental growth  methylcytosine dioxygenase activity  oxidative demethylation  DNA demethylation  
Ontology : EGO-EBIin utero embryonic development  neuron migration  placenta development  DNA-(apurinic or apyrimidinic site) lyase activity  nuclear euchromatin  mitochondrion  DNA repair  DNA dealkylation involved in DNA repair  ferrous iron binding  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen  neuron projection development  chemoattractant activity  RNA repair  developmental growth  methylcytosine dioxygenase activity  oxidative demethylation  DNA demethylation  
Other databases
Probes
Litterature
PubMed11 Pubmed reference(s) in Entrez
PubGeneALKBH1
iHOPALKBH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:47:30 CEST 2013
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