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ALKBH1 (alkB, alkylation repair homolog 1 (E. coli))

Identity

Other namesABH
ABH1
ALKBH
alkB
hABH
HGNC (Hugo) ALKBH1
LocusID (NCBI) 8846
Location 14q24.3
Location_base_pair Starts at 78138749 and ends at 78174356 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)ALKBH1   17911
Cards
Entrez_Gene (NCBI)ALKBH1  8846  alkB, alkylation repair homolog 1 (E. coli)
GeneCards (Weizmann)ALKBH1
Ensembl (Hinxton)ENSG00000100601 [Gene_View]  chr14:78138749-78174356 [Contig_View]  ALKBH1 [Vega]
ICGC DataPortalENSG00000100601
cBioPortalALKBH1
AceView (NCBI)ALKBH1
Genatlas (Paris)ALKBH1
WikiGenes8846
SOURCE (Princeton)NM_001039506 NM_006020
Genomic and cartography
GoldenPath (UCSC)ALKBH1  -  14q24.3   chr14:78138749-78174356 -  14q24.3   [Description]    (hg19-Feb_2009)
EnsemblALKBH1 - 14q24.3 [CytoView]
Mapping of homologs : NCBIALKBH1 [Mapview]
OMIM605345   
Gene and transcription
Genbank (Entrez)BC015024 BC025787 BX537699 DQ890543 DQ893703
RefSeq transcript (Entrez)NM_001039506 NM_006020
RefSeq genomic (Entrez)AC_000146 NC_000014 NC_018925 NT_026437 NW_001838113 NW_004929393
Consensus coding sequences : CCDS (NCBI)ALKBH1
Cluster EST : UnigeneHs.94542 [ NCBI ]
CGAP (NCI)Hs.94542
Alternative Splicing : Fast-db (Paris)GSHG0009522
Alternative Splicing GalleryENSG00000100601
Gene ExpressionALKBH1 [ NCBI-GEO ]     ALKBH1 [ SEEK ]   ALKBH1 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ13686 (Uniprot)
NextProtQ13686  [Medical]
With graphics : InterProQ13686
Splice isoforms : SwissVarQ13686 (Swissvar)
Catalytic activity : Enzyme1.14.11.33 [ Enzyme-Expasy ]   1.14.11.331.14.11.33 [ IntEnz-EBI ]   1.14.11.33 [ BRENDA ]   1.14.11.33 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)FE2OG_OXY (PS51471)   
Domains : Interpro (EBI)Alkb [organisation]   AlkB-like [organisation]   Oxoglu/Fe-dep_dioxygenase [organisation]  
Related proteins : CluSTrQ13686
Domain families : Pfam (Sanger)2OG-FeII_Oxy_2 (PF13532)   
Domain families : Pfam (NCBI)pfam13532   
DMDM Disease mutations8846
Blocks (Seattle)Q13686
Human Protein AtlasENSG00000100601 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ13686
IPIIPI00014482   IPI01025939   IPI01026048   
Protein Interaction databases
DIP (DOE-UCLA)Q13686
IntAct (EBI)Q13686
FunCoupENSG00000100601
BioGRIDALKBH1
InParanoidQ13686
Interologous Interaction database Q13686
IntegromeDBALKBH1
STRING (EMBL)ALKBH1
Ontologies - Pathways
Ontology : AmiGODNA catabolic process, endonucleolytic  DNA catabolic process, endonucleolytic  in utero embryonic development  neuron migration  placenta development  DNA-(apurinic or apyrimidinic site) lyase activity  nuclear euchromatin  mitochondrion  DNA repair  DNA dealkylation involved in DNA repair  ferrous iron binding  neuron projection development  chemoattractant activity  RNA repair  negative regulation of neuron apoptotic process  developmental growth  positive chemotaxis  methylcytosine dioxygenase activity  oxidative demethylation  DNA demethylation  
Ontology : EGO-EBIDNA catabolic process, endonucleolytic  DNA catabolic process, endonucleolytic  in utero embryonic development  neuron migration  placenta development  DNA-(apurinic or apyrimidinic site) lyase activity  nuclear euchromatin  mitochondrion  DNA repair  DNA dealkylation involved in DNA repair  ferrous iron binding  neuron projection development  chemoattractant activity  RNA repair  negative regulation of neuron apoptotic process  developmental growth  positive chemotaxis  methylcytosine dioxygenase activity  oxidative demethylation  DNA demethylation  
Protein Interaction DatabaseALKBH1
Wikipedia pathwaysALKBH1
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)ALKBH1
snp3D : Map Gene to Disease8846
SNP (GeneSNP Utah)ALKBH1
SNP : HGBaseALKBH1
Genetic variants : HAPMAPALKBH1
Exome VariantALKBH1
1000_GenomesALKBH1 
ICGC programENSG00000100601 
Somatic Mutations in Cancer : COSMICALKBH1 
CONAN: Copy Number AnalysisALKBH1 
Mutations and Diseases : HGMDALKBH1
Mutations and Diseases : intOGenALKBH1
Genomic VariantsALKBH1  ALKBH1 [DGVbeta]
dbVarALKBH1
ClinVarALKBH1
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM605345   
MedgenALKBH1
GENETestsALKBH1
Disease Genetic AssociationALKBH1
Huge Navigator ALKBH1 [HugePedia]  ALKBH1 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneALKBH1
Homology/Alignments : Family Browser (UCSC)ALKBH1
Phylogenetic Trees/Animal Genes : TreeFamALKBH1
Chemical/Protein Interactions : CTD8846
Chemical/Pharm GKB GenePA134906996
Clinical trialALKBH1
Cancer Resource (Charite)ENSG00000100601
Other databases
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
CoreMineALKBH1
iHOPALKBH1
OncoSearchALKBH1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Aug 26 16:37:51 CEST 2014

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