ALKBH1 (alkB homolog 1, histone H2A dioxygenase)

2012-12-01  

Identity

HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
ABH,ABH1,ALKBH,alkB,hABH
FUSION GENES

Other Information

Locus ID:

NCBI: 8846
MIM: 605345
HGNC: 17911
Ensembl: ENSG00000100601

Variants:

dbSNP: 8846
ClinVar: 8846
TCGA: ENSG00000100601
COSMIC: ALKBH1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100601ENST00000216489Q13686
ENSG00000100601ENST00000555100H0YJF3
ENSG00000100601ENST00000557057G3V4M4

Expression (GTEx)

0
5
10
15

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
362283192023Evaluating the Potential for ABO-incompatible Islet Transplantation: Expression of ABH Antigens on Human Pancreata, Isolated Islets, and Embryonic Stem Cell-derived Islets.0
369203402023ALKBH1 contributes to renal cell carcinoma progression by reducing N6-methyladenine of GPR137.7
369764982023DNA 6mA demethylase ALKBH1 regulates DDX18 expression to promote proliferation of human head and neck squamous cell carcinoma.3
369891112023The N(6)-methyladenine DNA demethylase ALKBH1 promotes gastric carcinogenesis by disrupting NRF1 binding capacity.8
362283192023Evaluating the Potential for ABO-incompatible Islet Transplantation: Expression of ABH Antigens on Human Pancreata, Isolated Islets, and Embryonic Stem Cell-derived Islets.0
369203402023ALKBH1 contributes to renal cell carcinoma progression by reducing N6-methyladenine of GPR137.7
369764982023DNA 6mA demethylase ALKBH1 regulates DDX18 expression to promote proliferation of human head and neck squamous cell carcinoma.3
369891112023The N(6)-methyladenine DNA demethylase ALKBH1 promotes gastric carcinogenesis by disrupting NRF1 binding capacity.8
349229432022DNA demethylase ALKBH1 promotes adipogenic differentiation via regulation of HIF-1 signaling.12
349229432022DNA demethylase ALKBH1 promotes adipogenic differentiation via regulation of HIF-1 signaling.12
330685532021ALKBH1 promotes lung cancer by regulating m6A RNA demethylation.27
332318442021A positive feedback loop between AlkB homolog 5 and miR-193a-3p promotes growth and metastasis in esophageal squamous cell carcinoma.16
340038002021ALKBH1-demethylated DNA N6-methyladenine modification triggers vascular calcification via osteogenic reprogramming in chronic kidney disease.29
340468492021Demethyltransferase AlkBH1 substrate diversity and relationship to human diseases.8
330685532021ALKBH1 promotes lung cancer by regulating m6A RNA demethylation.27

Citation

Dessen P

ALKBH1 (alkB homolog 1, histone H2A dioxygenase)

Atlas Genet Cytogenet Oncol Haematol. 2012-12-01

Online version: http://atlasgeneticsoncology.org/gene/53071/alkbh1