Identity
HGNC
LOCATION
14q24.3
LOCUSID
ALIAS
ABH,ABH1,ALKBH,alkB,hABH
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8846
MIM: 605345
HGNC: 17911
Ensembl: ENSG00000100601
Variants:
dbSNP: 8846
ClinVar: 8846
TCGA: ENSG00000100601
COSMIC: ALKBH1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000100601 | ENST00000216489 | Q13686 |
| ENSG00000100601 | ENST00000555100 | H0YJF3 |
| ENSG00000100601 | ENST00000557057 | G3V4M4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36228319 | 2023 | Evaluating the Potential for ABO-incompatible Islet Transplantation: Expression of ABH Antigens on Human Pancreata, Isolated Islets, and Embryonic Stem Cell-derived Islets. | 0 |
| 36920340 | 2023 | ALKBH1 contributes to renal cell carcinoma progression by reducing N6-methyladenine of GPR137. | 7 |
| 36976498 | 2023 | DNA 6mA demethylase ALKBH1 regulates DDX18 expression to promote proliferation of human head and neck squamous cell carcinoma. | 3 |
| 36989111 | 2023 | The N(6)-methyladenine DNA demethylase ALKBH1 promotes gastric carcinogenesis by disrupting NRF1 binding capacity. | 8 |
| 36228319 | 2023 | Evaluating the Potential for ABO-incompatible Islet Transplantation: Expression of ABH Antigens on Human Pancreata, Isolated Islets, and Embryonic Stem Cell-derived Islets. | 0 |
| 36920340 | 2023 | ALKBH1 contributes to renal cell carcinoma progression by reducing N6-methyladenine of GPR137. | 7 |
| 36976498 | 2023 | DNA 6mA demethylase ALKBH1 regulates DDX18 expression to promote proliferation of human head and neck squamous cell carcinoma. | 3 |
| 36989111 | 2023 | The N(6)-methyladenine DNA demethylase ALKBH1 promotes gastric carcinogenesis by disrupting NRF1 binding capacity. | 8 |
| 34922943 | 2022 | DNA demethylase ALKBH1 promotes adipogenic differentiation via regulation of HIF-1 signaling. | 12 |
| 34922943 | 2022 | DNA demethylase ALKBH1 promotes adipogenic differentiation via regulation of HIF-1 signaling. | 12 |
| 33068553 | 2021 | ALKBH1 promotes lung cancer by regulating m6A RNA demethylation. | 27 |
| 33231844 | 2021 | A positive feedback loop between AlkB homolog 5 and miR-193a-3p promotes growth and metastasis in esophageal squamous cell carcinoma. | 16 |
| 34003800 | 2021 | ALKBH1-demethylated DNA N6-methyladenine modification triggers vascular calcification via osteogenic reprogramming in chronic kidney disease. | 29 |
| 34046849 | 2021 | Demethyltransferase AlkBH1 substrate diversity and relationship to human diseases. | 8 |
| 33068553 | 2021 | ALKBH1 promotes lung cancer by regulating m6A RNA demethylation. | 27 |
Citation
Dessen P
ALKBH1 (alkB homolog 1, histone H2A dioxygenase)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53071/alkbh1
