Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 121642
MIM: 610602
HGNC: 32487
Ensembl: ENSG00000189046
Variants:
dbSNP: 121642
ClinVar: 121642
TCGA: ENSG00000189046
COSMIC: ALKBH2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37508504 | 2023 | Individual Contributions of Amido Acid Residues Tyr122, Ile168, and Asp173 to the Activity and Substrate Specificity of Human DNA Dioxygenase ABH2. | 0 |
| 37508504 | 2023 | Individual Contributions of Amido Acid Residues Tyr122, Ile168, and Asp173 to the Activity and Substrate Specificity of Human DNA Dioxygenase ABH2. | 0 |
| 35956910 | 2022 | Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy. | 2 |
| 35956910 | 2022 | Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy. | 2 |
| 33161373 | 2020 | Insights into the Direct Oxidative Repair of Etheno Lesions: MD and QM/MM Study on the Substrate Scope of ALKBH2 and AlkB. | 5 |
| 33302959 | 2020 | ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-κB pathway. | 6 |
| 33161373 | 2020 | Insights into the Direct Oxidative Repair of Etheno Lesions: MD and QM/MM Study on the Substrate Scope of ALKBH2 and AlkB. | 5 |
| 33302959 | 2020 | ALKBH2 inhibition alleviates malignancy in colorectal cancer by regulating BMI1-mediated activation of NF-κB pathway. | 6 |
| 31114894 | 2019 | DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro. | 30 |
| 31114894 | 2019 | DNA repair enzymes ALKBH2, ALKBH3, and AlkB oxidize 5-methylcytosine to 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxylcytosine in vitro. | 30 |
| 26930515 | 2016 | Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions. | 12 |
| 26930515 | 2016 | Roles of Aag, Alkbh2, and Alkbh3 in the Repair of Carboxymethylated and Ethylated Thymidine Lesions. | 12 |
| 25797601 | 2015 | Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins. | 21 |
| 26408825 | 2015 | The interaction between ALKBH2 DNA repair enzyme and PCNA is direct, mediated by the hydrophobic pocket of PCNA and perturbed in naturally-occurring ALKBH2 variants. | 17 |
| 25797601 | 2015 | Differential repair of etheno-DNA adducts by bacterial and human AlkB proteins. | 21 |
Citation
Dessen P
ALKBH2 (alkB homolog 2, alpha-ketoglutarate dependent dioxygenase)
Atlas Genet Cytogenet Oncol Haematol. 2012-12-01
Online version: http://atlasgeneticsoncology.org/gene/53082/alkbh2
