Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 242
MIM: 603741
HGNC: 430
Ensembl: ENSG00000179477
Variants:
dbSNP: 242
ClinVar: 242
TCGA: ENSG00000179477
COSMIC: ALOX12B
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000179477 | ENST00000647874 | O75342 |
| ENSG00000179477 | ENST00000649809 | A0A3B3IRK2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38060040 | 2023 | Whole exome sequencing identifies novel pathogenic variants in TGM1 and ALOX12B in patients with hereditary ichthyosis. | 0 |
| 38060040 | 2023 | Whole exome sequencing identifies novel pathogenic variants in TGM1 and ALOX12B in patients with hereditary ichthyosis. | 0 |
| 35768785 | 2022 | Survival-related indicators ALOX12B and SPRR1A are associated with DNA damage repair and tumor microenvironment status in HPV 16-negative head and neck squamous cell carcinoma patients. | 6 |
| 35768785 | 2022 | Survival-related indicators ALOX12B and SPRR1A are associated with DNA damage repair and tumor microenvironment status in HPV 16-negative head and neck squamous cell carcinoma patients. | 6 |
| 33435499 | 2021 | Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients. | 11 |
| 33607042 | 2021 | Unbound Corneocyte Lipid Envelopes in 12R-Lipoxygenase Deficiency Support a Specific Role in Lipid-Protein Cross-Linking. | 3 |
| 33435499 | 2021 | Meta-Analysis of Mutations in ALOX12B or ALOXE3 Identified in a Large Cohort of 224 Patients. | 11 |
| 33607042 | 2021 | Unbound Corneocyte Lipid Envelopes in 12R-Lipoxygenase Deficiency Support a Specific Role in Lipid-Protein Cross-Linking. | 3 |
| 32253496 | 2020 | Mutation in ALOX12B likely cause of POI and also ichthyosis in a large Iranian pedigree. | 2 |
| 32253496 | 2020 | Mutation in ALOX12B likely cause of POI and also ichthyosis in a large Iranian pedigree. | 2 |
| 28236338 | 2017 | Summary of mutations underlying autosomal recessive congenital ichthyoses (ARCI) in Arabs with four novel mutations in ARCI-related genes from the United Arab Emirates. | 0 |
| 28236338 | 2017 | Summary of mutations underlying autosomal recessive congenital ichthyoses (ARCI) in Arabs with four novel mutations in ARCI-related genes from the United Arab Emirates. | 0 |
| 26575587 | 2016 | A novel deletion mutation in the ALOX12B gene in a Kurdish family with autosomal recessive congenital ichthyosis. | 0 |
| 26575587 | 2016 | A novel deletion mutation in the ALOX12B gene in a Kurdish family with autosomal recessive congenital ichthyosis. | 0 |
| 23954555 | 2014 | The role of lipoxygenases in epidermis. | 0 |
Citation
Dessen P
ALOX12B (arachidonate 12-lipoxygenase, 12R type)
Atlas Genet Cytogenet Oncol Haematol. 2010-02-01
Online version: http://atlasgeneticsoncology.org/gene/51324/alox12b
