| Nomenclature |
|---|
| HGNC (Hugo) | ALYREF 19071 |
| Cards |
|---|
| Entrez_Gene (NCBI) | ALYREF 10189 Aly/REF export factor |
| Aliases | ALY; ALY/REF; BEF; REF; |
| THOC4 |
| GeneCards (Weizmann) | ALYREF |
| Ensembl hg19 (Hinxton) | ENSG00000183684 [Gene_View] |
| Ensembl hg38 (Hinxton) | ENSG00000183684 [Gene_View] ENSG00000183684 [Sequence] chr17:81887835-81891586 [Contig_View] ALYREF [Vega] |
| ICGC DataPortal | ENSG00000183684 |
| TCGA cBioPortal | ALYREF |
| AceView (NCBI) | ALYREF |
| Genatlas (Paris) | ALYREF |
| WikiGenes | 10189 |
| SOURCE (Princeton) | ALYREF |
| Genetics Home Reference (NIH) | ALYREF |
| Genomic and cartography |
|---|
| GoldenPath hg38 (UCSC) | ALYREF - chr17:81887835-81891586 - 17q25.3 [Description] (hg38-Dec_2013) |
| GoldenPath hg19 (UCSC) | ALYREF - 17q25.3 [Description] (hg19-Feb_2009) |
| GoldenPath | ALYREF - 17q25.3 [CytoView hg19] ALYREF - 17q25.3 [CytoView hg38] |
| ImmunoBase | ENSG00000183684 |
| Mapping of homologs : NCBI | ALYREF [Mapview hg19] ALYREF [Mapview hg38] |
| OMIM | 604171 |
| Gene and transcription |
|---|
| Genbank (Entrez) | AF047002 AF086513 BC052302 BU624466 |
| RefSeq transcript (Entrez) | NM_005782 |
| RefSeq genomic (Entrez) | |
| Consensus coding sequences : CCDS (NCBI) | ALYREF |
| Cluster EST : Unigene | Hs.534385 [ NCBI ] |
| CGAP (NCI) | Hs.534385 |
| Alternative Splicing Gallery | ENSG00000183684 |
| Gene Expression | ALYREF [ NCBI-GEO ] ALYREF [ EBI - ARRAY_EXPRESS ]
ALYREF [ SEEK ] ALYREF [ MEM ] |
| Gene Expression Viewer (FireBrowse) | ALYREF [ Firebrowse - Broad ] |
| SOURCE (Princeton) | Expression in : [Datasets] [Normal Tissue Atlas] [carcinoma Classsification] [NCI60] |
| Genevestigator | Expression in : [tissues] [cell-lines] [cancer] [perturbations] |
| BioGPS (Tissue expression) | 10189 |
| GTEX Portal (Tissue expression) | ALYREF |
| Human Protein Atlas | ENSG00000183684-ALYREF [pathology] [cell] [tissue] |
| Protein : pattern, domain, 3D structure |
|---|
| UniProt/SwissProt | Q86V81 [function] [subcellular_location] [family_and_domains] [pathology_and_biotech] [ptm_processing] [expression] [interaction] |
| NextProt | Q86V81 [Sequence] [Exons] [Medical] [Publications] |
| With graphics : InterPro | Q86V81 |
| Splice isoforms : SwissVar | Q86V81 |
| PhosPhoSitePlus | Q86V81 |
| Domaine pattern : Prosite (Expaxy) | RRM (PS50102) |
| Domains : Interpro (EBI) | FoP_C Nucleotide-bd_a/b_plait_sf RBD_domain_sf RRM_dom |
| Domain families : Pfam (Sanger) | FoP_duplication (PF13865) RRM_1 (PF00076) |
| Domain families : Pfam (NCBI) | pfam13865 pfam00076 |
| Domain families : Smart (EMBL) | FoP_duplication (SM01218) RRM (SM00360) |
| Conserved Domain (NCBI) | ALYREF |
| DMDM Disease mutations | 10189 |
| Blocks (Seattle) | ALYREF |
| PDB (RSDB) | 3ULH |
| PDB Europe | 3ULH |
| PDB (PDBSum) | 3ULH |
| PDB (IMB) | 3ULH |
| Structural Biology KnowledgeBase | 3ULH |
| SCOP (Structural Classification of Proteins) | 3ULH |
| CATH (Classification of proteins structures) | 3ULH |
| Superfamily | Q86V81 |
| Human Protein Atlas [tissue] | ENSG00000183684-ALYREF [tissue] |
| Peptide Atlas | Q86V81 |
| HPRD | 09168 |
| IPI | IPI01010794 IPI00328840 |
| Protein Interaction databases |
|---|
| DIP (DOE-UCLA) | Q86V81 |
| IntAct (EBI) | Q86V81 |
| FunCoup | ENSG00000183684 |
| BioGRID | ALYREF |
| STRING (EMBL) | ALYREF |
| ZODIAC | ALYREF |
| Ontologies - Pathways |
|---|
| QuickGO | Q86V81 |
| Ontology : AmiGO | regulation of DNA recombination transcription export complex mRNA splicing, via spliceosome mRNA splicing, via spliceosome nuclear chromosome, telomeric region osteoblast differentiation RNA binding protein binding nucleoplasm cytosol RNA export from nucleus mRNA export from nucleus mRNA export from nucleus membrane viral process nuclear speck mRNA 3'-end processing replication fork processing positive regulation of DNA-templated transcription, elongation exon-exon junction complex viral mRNA export from host cell nucleus extracellular exosome catalytic step 2 spliceosome |
| Ontology : EGO-EBI | regulation of DNA recombination transcription export complex mRNA splicing, via spliceosome mRNA splicing, via spliceosome nuclear chromosome, telomeric region osteoblast differentiation RNA binding protein binding nucleoplasm cytosol RNA export from nucleus mRNA export from nucleus mRNA export from nucleus membrane viral process nuclear speck mRNA 3'-end processing replication fork processing positive regulation of DNA-templated transcription, elongation exon-exon junction complex viral mRNA export from host cell nucleus extracellular exosome catalytic step 2 spliceosome |
| Pathways : KEGG | RNA transport mRNA surveillance pathway Spliceosome Herpes simplex infection |
| NDEx Network | ALYREF |
| Atlas of Cancer Signalling Network | ALYREF |
| Wikipedia pathways | ALYREF |
| Orthology - Evolution |
|---|
| OrthoDB | 10189 |
| GeneTree (enSembl) | ENSG00000183684 |
| Phylogenetic Trees/Animal Genes : TreeFam | ALYREF |
| HOGENOM | Q86V81 |
| Homologs : HomoloGene | ALYREF |
| Homology/Alignments : Family Browser (UCSC) | ALYREF |
| Gene fusions - Rearrangements |
|---|
| Fusion : Quiver | ALYREF |
| Polymorphisms : SNP and Copy number variants |
|---|
| NCBI Variation Viewer | ALYREF [hg38] |
| dbSNP Single Nucleotide Polymorphism (NCBI) | ALYREF |
| dbVar | ALYREF |
| ClinVar | ALYREF |
| 1000_Genomes | ALYREF |
| Exome Variant Server | ALYREF |
| ExAC (Exome Aggregation Consortium) | ENSG00000183684 |
| GNOMAD Browser | ENSG00000183684 |
| Varsome Browser | ALYREF |
| Genetic variants : HAPMAP | 10189 |
| Genomic Variants (DGV) | ALYREF [DGVbeta] |
| DECIPHER | ALYREF [patients] [syndromes] [variants] [genes] |
| CONAN: Copy Number Analysis | ALYREF |
| Mutations |
|---|
| ICGC Data Portal | ALYREF |
| TCGA Data Portal | ALYREF |
| Broad Tumor Portal | ALYREF |
| OASIS Portal | ALYREF [ Somatic mutations - Copy number] |
| Somatic Mutations in Cancer : COSMIC | ALYREF [overview] [genome browser] [tissue] [distribution] |
| Somatic Mutations in Cancer : COSMIC3D | ALYREF |
| Mutations and Diseases : HGMD | ALYREF |
| LOVD (Leiden Open Variation Database) | Whole genome datasets |
| LOVD (Leiden Open Variation Database) | LOVD 3.0 shared installation |
| BioMuta | search ALYREF |
| DgiDB (Drug Gene Interaction Database) | ALYREF |
| DoCM (Curated mutations) | ALYREF (select the gene name) |
| CIViC (Clinical Interpretations of Variants in Cancer) | ALYREF (select a term) |
| intoGen | ALYREF |
| Cancer3D | ALYREF(select the gene name) |
| Impact of mutations | [PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser] |
| Diseases |
|---|
| OMIM | 604171 |
| Orphanet | |
| DisGeNET | ALYREF |
| Medgen | ALYREF |
| Genetic Testing Registry | ALYREF
|
| NextProt | Q86V81 [Medical] |
| TSGene | 10189 |
| GENETests | ALYREF |
| Target Validation | ALYREF |
| Huge Navigator |
ALYREF [HugePedia] |
| snp3D : Map Gene to Disease | 10189 |
| BioCentury BCIQ | ALYREF |
| ClinGen | ALYREF |
| Clinical trials, drugs, therapy |
|---|
| Chemical/Protein Interactions : CTD | 10189 |
| Chemical/Pharm GKB Gene | PA134925107 |
| Clinical trial | ALYREF |
| Miscellaneous |
|---|
| canSAR (ICR) | ALYREF (select the gene name) |
| DataMed Index | ALYREF |
| Probes |
|---|
| Litterature |
|---|
| PubMed | 148 Pubmed reference(s) in Entrez |
| GeneRIFs | Gene References Into Functions (Entrez) |
| CoreMine | ALYREF |
| EVEX | ALYREF |
| GoPubMed | ALYREF |
| iHOP | ALYREF |
