AMY1B (amylase alpha 1B)

2014-11-01  

Identity

HGNC
LOCATION
1p21.1
LOCUSID
ALIAS
AMY1

Other Information

Locus ID:

NCBI: 277
MIM: 104701
HGNC: 475
Ensembl: ENSG00000174876

Variants:

dbSNP: 277
ClinVar: 277
TCGA: ENSG00000174876
COSMIC: AMY1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000174876ENST00000330330P04745
ENSG00000174876ENST00000370080P04745
ENSG00000174876ENST00000425410Q5T084
ENSG00000174876ENST00000446703Q5T085

Expression (GTEx)

0
1
2
3
4
5
6
7
8
9
10

Pathways

PathwaySourceExternal ID
Starch and sucrose metabolismKEGGko00500
Starch and sucrose metabolismKEGGhsa00500
Metabolic pathwaysKEGGhsa01100
Salivary secretionKEGGko04970
Salivary secretionKEGGhsa04970
Carbohydrate digestion and absorptionKEGGko04973
Carbohydrate digestion and absorptionKEGGhsa04973
MetabolismREACTOMER-HSA-1430728
Metabolism of carbohydratesREACTOMER-HSA-71387
Digestion of dietary carbohydrateREACTOMER-HSA-189085

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
220636482012Salivary alpha-amylase and cortisol responsiveness following electrical stimulation stress in major depressive disorder patients.12
218278212011State and trait variance in salivary α-amylase: a behavioral genetic study.7
255887012015Salivary alpha amylase diurnal pattern and stress response are associated with body mass index in low-income preschool-aged children.7
282194102017Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity.3
309828602019Salivary α-amylase copy number is not associated with weight trajectories and glycemic improvements following clinical weight loss: results from a 2-phase dietary intervention study.1
161527702005On the genetic polymorphism of the serum alpha-amylase in the population of the south western Bulgaria (second communication).0

Citation

Dessen P

AMY1B (amylase alpha 1B)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60281/amy1b