Identity
HGNC
LOCATION
2q13
LOCUSID
ALIAS
APC1,MCPR,TSG24
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 64682
MIM: 608473
HGNC: 19988
Ensembl: ENSG00000153107
Variants:
dbSNP: 64682
ClinVar: 64682
TCGA: ENSG00000153107
COSMIC: ANAPC1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35956818 | 2022 | Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1. | 0 |
| 35956818 | 2022 | Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1. | 0 |
| 33082289 | 2020 | Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. | 6 |
| 33082289 | 2020 | Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S. | 6 |
| 30482618 | 2019 | Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division. | 62 |
| 30894546 | 2019 | Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. | 18 |
| 31303264 | 2019 | Mutations in ANAPC1, Encoding a Scaffold Subunit of the Anaphase-Promoting Complex, Cause Rothmund-Thomson Syndrome Type 1. | 22 |
| 30482618 | 2019 | Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division. | 62 |
| 30894546 | 2019 | Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density. | 18 |
| 31303264 | 2019 | Mutations in ANAPC1, Encoding a Scaffold Subunit of the Anaphase-Promoting Complex, Cause Rothmund-Thomson Syndrome Type 1. | 22 |
| 28505105 | 2017 | New Functions of APC/C Ubiquitin Ligase in the Nervous System and Its Role in Alzheimer's Disease. | 14 |
| 28505105 | 2017 | New Functions of APC/C Ubiquitin Ligase in the Nervous System and Its Role in Alzheimer's Disease. | 14 |
| 27601667 | 2016 | WD40 domain of Apc1 is critical for the coactivator-induced allosteric transition that stimulates APC/C catalytic activity. | 12 |
| 27655696 | 2016 | Identification of the APC/C co-factor FZR1 as a novel therapeutic target for multiple myeloma. | 14 |
| 27939943 | 2016 | The Mitotic Checkpoint Complex Requires an Evolutionary Conserved Cassette to Bind and Inhibit Active APC/C. | 23 |
Citation
Dessen P
ANAPC1 (anaphase promoting complex subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2007-04-01
Online version: http://atlasgeneticsoncology.org/gene/47289/anapc1
