ANKS1B (ankyrin repeat and sterile alpha motif domain containing 1B)

2003-02-01  

Identity

HGNC
LOCATION
12q23.1
LOCUSID
ALIAS
AIDA,AIDA-1,ANKS2,EB-1,EB1,cajalin-2
FUSION GENES

Other Information

Locus ID:

NCBI: 56899
MIM: 607815
HGNC: 24600
Ensembl: ENSG00000185046

Variants:

dbSNP: 56899
ClinVar: 56899
TCGA: ENSG00000185046
COSMIC: ANKS1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000185046ENST00000329257J3QSU0
ENSG00000185046ENST00000333732F8VR14
ENSG00000185046ENST00000341752Q7Z6G8
ENSG00000185046ENST00000546364R4GN78
ENSG00000185046ENST00000546568Q7Z6G8
ENSG00000185046ENST00000546960Q7Z6G8
ENSG00000185046ENST00000547010Q7Z6G8
ENSG00000185046ENST00000547362R4GMN5
ENSG00000185046ENST00000547446Q7Z6G8
ENSG00000185046ENST00000547776Q7Z6G8
ENSG00000185046ENST00000548447R4GN73
ENSG00000185046ENST00000549025Q7Z6G8
ENSG00000185046ENST00000549493Q7Z6G8
ENSG00000185046ENST00000549558Q7Z6G8
ENSG00000185046ENST00000549797R4GMQ4
ENSG00000185046ENST00000549866F8VVQ4
ENSG00000185046ENST00000550693Q7Z6G8
ENSG00000185046ENST00000550778H0YI72
ENSG00000185046ENST00000551560R4GNJ0
ENSG00000185046ENST00000551613R4GN70
ENSG00000185046ENST00000552407R4GMS8
ENSG00000185046ENST00000552748R4GN07
ENSG00000185046ENST00000555119H0YJZ1

Expression (GTEx)

0
5
10
15
20
25

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA162565877amisulprideChemicalClinicalAnnotationassociatedPD28332719
PA166119022methamphetamine dependenceDiseaseClinicalAnnotationassociatedPD31462767
PA443309AlcoholismDiseaseClinicalAnnotationassociatedPD31462767
PA444460Heroin DependenceDiseaseClinicalAnnotationassociatedPD31462767
PA447216SchizophreniaDiseaseClinicalAnnotationassociatedPD28332719
PA448073ethanolChemicalClinicalAnnotationassociatedPD31462767
PA450403methamphetamineChemicalClinicalAnnotationassociatedPD31462767
PA452619heroinChemicalClinicalAnnotationassociatedPD31462767

References

Pubmed IDYearTitleCitations
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.85
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
198514622009EB1 recognizes the nucleotide state of tubulin in the microtubule lattice.57
304540102018The pro-metastasis effect of circANKS1B in breast cancer.37
124151132002Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.24
153476842004Amyloid-beta protein precursor (AbetaPP) intracellular domain-associated protein-1 proteins bind to AbetaPP and modulate its processing in an isoform-specific manner.21
150043292004The intracellular localization of amyloid beta protein precursor (AbetaPP) intracellular domain associated protein-1 (AIDA-1) is regulated by AbetaPP and alternative splicing.15
127000342003E2A basic helix-loop-helix transcription factors in human leukemia.12
196660312009A nuclear localization signal at the SAM-SAM domain interface of AIDA-1 suggests a requirement for domain uncoupling prior to nuclear import.11
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.11

Citation

Dessen P

ANKS1B (ankyrin repeat and sterile alpha motif domain containing 1B)

Atlas Genet Cytogenet Oncol Haematol. 2003-02-01

Online version: http://atlasgeneticsoncology.org/gene/40391/anks1b