Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 339
MIM: 600130
HGNC: 604
Ensembl: ENSG00000111701
Variants:
dbSNP: 339
ClinVar: 339
TCGA: ENSG00000111701
COSMIC: APOBEC1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111701 | ENST00000229304 | P41238 |
| ENSG00000111701 | ENST00000467171 | A0A0B4J232 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Gene Expression | REACTOME | R-HSA-74160 |
| mRNA Editing | REACTOME | R-HSA-75072 |
| mRNA Editing: C to U Conversion | REACTOME | R-HSA-72200 |
| Formation of the Editosome | REACTOME | R-HSA-75094 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36702998 | 2023 | APOBEC mutagenesis is a common process in normal human small intestine. | 9 |
| 38708190 | 2023 | Identification of RBM46 as a novel APOBEC1 cofactor for C-to-U RNA-editing activity. | 0 |
| 36702998 | 2023 | APOBEC mutagenesis is a common process in normal human small intestine. | 9 |
| 38708190 | 2023 | Identification of RBM46 as a novel APOBEC1 cofactor for C-to-U RNA-editing activity. | 0 |
| 36100631 | 2022 | The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness. | 40 |
| 36100631 | 2022 | The roles of APOBEC-mediated RNA editing in SARS-CoV-2 mutations, replication and fitness. | 40 |
| 33330905 | 2021 | APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A. | 13 |
| 33602235 | 2021 | Harnessing A3G for efficient and selective C-to-T conversion at C-rich sequences. | 0 |
| 33330905 | 2021 | APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A. | 13 |
| 33602235 | 2021 | Harnessing A3G for efficient and selective C-to-T conversion at C-rich sequences. | 0 |
| 29346513 | 2018 | Pancancer analysis identifies prognostic high-APOBEC1 expression level implicated in cancer in-frame insertions and deletions. | 15 |
| 29346513 | 2018 | Pancancer analysis identifies prognostic high-APOBEC1 expression level implicated in cancer in-frame insertions and deletions. | 15 |
| 28639893 | 2017 | Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells. | 3 |
| 28639893 | 2017 | Apobec-1 complementation factor regulates cell migration and apoptosis through Dickkopf1 by acting on its 3' untranslated region in MCF7 cells. | 3 |
| 25839328 | 2015 | Genomic analyses reveal mutational signatures and frequently altered genes in esophageal squamous cell carcinoma. | 184 |
Citation
Dessen P
APOBEC1 (apolipoprotein B mRNA editing enzyme catalytic subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-05-01
Online version: http://atlasgeneticsoncology.org/gene/676/apobec1
