APOL3 (apolipoprotein L3)

2003-06-01  

Identity

HGNC
APOL3
LOCATION
22q12.3
LOCUSID
80833
ALIAS
APOLIII,CG121,CG12_1,apoL-III
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 80833
MIM: 607253
HGNC: 14868
Ensembl: ENSG00000128284

Variants:

dbSNP: 80833
ClinVar: 80833
TCGA: ENSG00000128284
COSMIC: APOL3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128284ENST00000349314O95236
ENSG00000128284ENST00000361710O95236
ENSG00000128284ENST00000397287O95236
ENSG00000128284ENST00000397289H7BYQ5
ENSG00000128284ENST00000397293O95236
ENSG00000128284ENST00000422426F2Z2M3
ENSG00000128284ENST00000424878O95236
ENSG00000128284ENST00000424878A0A024R1G6
ENSG00000128284ENST00000426939H0YDW3
ENSG00000128284ENST00000432700F2Z2M3
ENSG00000128284ENST00000472303H0YD32
ENSG00000128284ENST00000487355H0YDH5
ENSG00000128284ENST00000487783H0YEQ0
ENSG00000128284ENST00000530895H0YEJ6
ENSG00000128284ENST00000531095H0YCT0
ENSG00000128284ENST00000531195H0YDW3

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
119449862002The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue.61
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.27
206311552010Family-based association analysis of 42 hereditary prostate cancer families identifies the Apolipoprotein L3 region on chromosome 22q12 as a risk locus.7
206311552010Family-based association analysis of 42 hereditary prostate cancer families identifies the Apolipoprotein L3 region on chromosome 22q12 as a risk locus.7
283399112018A null variant in the apolipoprotein L3 gene is associated with non-diabetic nephropathy.6
206026152010Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?2
304234772018Apoliporotein L3 interferes with endothelial tube formation via regulation of ERK1/2, FAK and Akt signaling pathway.2

Citation

Dessen P

APOL3 (apolipoprotein L3)

Atlas Genet Cytogenet Oncol Haematol. 2003-06-01

Online version: http://atlasgeneticsoncology.org/gene/678/apol3