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APRT (adenine phosphoribosyltransferase)

Identity

Other namesAMP
APRTD
HGNC (Hugo) APRT
LocusID (NCBI) 353
Location 16q24.3
Location_base_pair Starts at 88875877 and ends at 88878342 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)APRT   626
Entrez_Gene (NCBI)APRT  353  adenine phosphoribosyltransferase
Cards
GeneCards (Weizmann)APRT
Ensembl (Hinxton)ENSG00000198931 [Gene_View]  chr16:88875877-88878342 [Contig_View]  APRT [Vega]
AceView (NCBI)APRT
Genatlas (Paris)APRT
SOURCE (Stanford)NM_000485 NM_001030018
Genomic and cartography
GoldenPath (UCSC)APRT  -  16q24.3   chr16:88875877-88878342 -  16q24.3   [Description]    (hg19-Feb_2009)
EnsemblAPRT - 16q24.3 [CytoView]
Mapping of homologs : NCBIAPRT [Mapview]
OMIM102600   614723   
Gene and transcription
Genbank (Entrez)BC106894 BC106895 BC107151 BM423481 BM550173
RefSeq transcript (SRS)NM_000485 NM_001030018
RefSeq transcript (Entrez)NM_000485 NM_001030018
RefSeq genomic (SRS)AC_000148 NC_000016 NC_018927 NG_008013 NT_010542 NW_001838334 NW_004078088
RefSeq genomic (Entrez)AC_000148 NC_000016 NC_018927 NG_008013 NT_010542 NW_001838334 NW_004078088
Consensus coding sequences : CCDS (NCBI)APRT
Cluster EST : UnigeneHs.28914 [ SRS ] Hs.28914 [ NCBI ]
CGAP (NCI)Hs.28914
Alternative Splicing : Fast-db (Paris)GSHG0012072
Alternative Splicing GalleryENSG00000198931
Gene ExpressionAPRT [ NCBI-GEO ]   APRT [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07741 (SRS) P07741 (Uniprot)
NextProtP07741
With graphics : InterProP07741
Splice isoforms : SwissVarP07741(Swissvar)
Domaine pattern : Prosite (SRS)PUR_PYR_PR_TRANSFER (PS00103)   
Domaine pattern : Prosite (Expaxy)PUR_PYR_PR_TRANSFER (PS00103)   
Domains : Interpro (SRS)Ade_phspho_trans    PRibTrfase_dom   
Domains : Interpro (EBI)Ade_phspho_trans    PRibTrfase_dom   
Related proteins : CluSTrP07741
Domain families : Pfam (SRS)Pribosyltran (PF00156)   
Domain families : Pfam (Sanger)Pribosyltran (PF00156)   
Domain families : Pfam (NCBI)pfam00156   
DMDM353
Blocks (Seattle)P07741
PDB (SRS)1OPU    1ORE    1ZN7    1ZN8    1ZN9   
PDB (PDBSum)1OPU    1ORE    1ZN7    1ZN8    1ZN9   
PDB (IMB)1OPU    1ORE    1ZN7    1ZN8    1ZN9   
PDB (RSDB)1OPU    1ORE    1ZN7    1ZN8    1ZN9   
Human Protein AtlasENSG00000198931
HPRD00029
IPIIPI00218693   IPI00816267   IPI00642457   
Protein Interaction databases
DIP (DOE-UCLA)P07741
IntAct (EBI)P07741
FunCoupENSG00000198931
REACTOMEAPRT
Protein Interaction Database353
BioGRIDAPRT
InParanoidP07741
Interologous Interaction database P07741
IntegromeDBAPRT
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)APRT
SNP (GeneSNP Utah)APRT
SNP : HGBaseAPRT
Genetic variants : HAPMAPAPRT
Somatic Mutations in Cancer : COSMICAPRT 
CONAN: Copy Number AnalysisAPRT 
Mutations and Diseases : HGMDAPRT
OMIM102600    614723   
GENETests102600    614723   
Disease Genetic AssociationAPRT
Huge Navigator APRT [HugePedia]  APRT [HugeCancerGEM]
Genomic VariantsAPRT  APRT [DGVbeta]
snp3D : Map Gene to Disease353
General knowledge
Homologs : HomoloGeneAPRT
Homology/Alignments : Family Browser (UCSC)APRT
Phylogenetic Trees/Animal Genes : TreeFamAPRT
Chemical/Protein Interactions : CTD353
Chemical/Pharm GKB GenePA24914
Clinical trialAPRT
Cancer Resource (Charite)ENSG00000198931
Ontology : AmiGOadenine binding  adenine phosphoribosyltransferase activity  nucleus  nucleolus  cytoplasm  cytoplasm  cytosol  purine nucleobase metabolic process  purine ribonucleoside salvage  adenine salvage  lactation  grooming behavior  AMP binding  purine-containing compound salvage  AMP salvage  small molecule metabolic process  nucleobase-containing small molecule metabolic process  
Ontology : EGO-EBIadenine binding  adenine phosphoribosyltransferase activity  nucleus  nucleolus  cytoplasm  cytoplasm  cytosol  purine nucleobase metabolic process  purine ribonucleoside salvage  adenine salvage  lactation  grooming behavior  AMP binding  purine-containing compound salvage  AMP salvage  small molecule metabolic process  nucleobase-containing small molecule metabolic process  
Pathways : KEGGPurine metabolism
Other databases
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
PubGeneAPRT
iHOPAPRT
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:28:54 CEST 2013
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