ARF5 (ADP ribosylation factor 5)

2006-10-01 Affiliation

Identity

HGNC

ARF5

LOCATION

7q32.1

LOCUSID

381

ALIAS

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 381
MIM: 103188
HGNC: 658
Ensembl: ENSG00000004059

Variants:

dbSNP: 381
ClinVar: 381
TCGA: ENSG00000004059
COSMIC: ARF5

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000004059	ENST00000000233	P84085
ENSG00000004059	ENST00000000233	A4D0Z3
ENSG00000004059	ENST00000415666	C9J1Z8

Expression (GTEx)

100

150

200

250

300

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Endocytosis	KEGG	ko04144
Endocytosis	KEGG	hsa04144
Metabolism of proteins	REACTOME	R-HSA-392499
Post-translational protein modification	REACTOME	R-HSA-597592
Asparagine N-linked glycosylation	REACTOME	R-HSA-446203
Transport to the Golgi and subsequent modification	REACTOME	R-HSA-948021
ER to Golgi Anterograde Transport	REACTOME	R-HSA-199977
Vesicle-mediated transport	REACTOME	R-HSA-5653656
Membrane Trafficking	REACTOME	R-HSA-199991
COPI-mediated anterograde transport	REACTOME	R-HSA-6807878
Intra-Golgi and retrograde Golgi-to-ER traffic	REACTOME	R-HSA-6811442
Golgi-to-ER retrograde transport	REACTOME	R-HSA-8856688
COPI-dependent Golgi-to-ER retrograde traffic	REACTOME	R-HSA-6811434

References

Pubmed ID	Year	Title	Citations
22105072	2012	Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses.	25
22815487	2012	BRAG2/GEP100/IQSec1 interacts with clathrin and regulates α5β1 integrin endocytosis through activation of ADP ribosylation factor 5 (Arf5).	22
22360420	2012	Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.	18
22573888	2012	ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5.	12
22185782	2011	GBF1-Arf-COPI-ArfGAP-mediated Golgi-to-ER transport involved in regulation of lipid homeostasis.	10
26000619	2015	GORAB Missense Mutations Disrupt RAB6 and ARF5 Binding and Golgi Targeting.	8
30655362	2019	Rab1b and ARF5 are novel RNA-binding proteins involved in FMDV IRES-driven RNA localization.	2

Citation

Dessen P

ARF5 (ADP ribosylation factor 5)

Atlas Genet Cytogenet Oncol Haematol. 2006-10-01

Online version: http://atlasgeneticsoncology.org/gene/43126/arf5