Identity
HGNC
LOCATION
10q11.22
LOCUSID
ALIAS
RhoGAP2,RhoGap22
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 58504
MIM: 610585
HGNC: 30320
Ensembl: ENSG00000128805
Variants:
dbSNP: 58504
ClinVar: 58504
TCGA: ENSG00000128805
COSMIC: ARHGAP22
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Signal Transduction | REACTOME | R-HSA-162582 |
| Signaling by Rho GTPases | REACTOME | R-HSA-194315 |
| Rho GTPase cycle | REACTOME | R-HSA-194840 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36456117 | 2022 | Endosomal Localization of RacGAP Protein ARHGAP22 Regulates its GAP Activity in Human Melanoma Cells. | 0 |
| 36456117 | 2022 | Endosomal Localization of RacGAP Protein ARHGAP22 Regulates its GAP Activity in Human Melanoma Cells. | 0 |
| 31602702 | 2020 | DNA hypermethylation is associated with invasive phenotype of malignant melanoma. | 29 |
| 31976761 | 2020 | Associations of rs2300782 CAMK4, rs2292239 ERBB3 and rs10491034 ARHGAP22 with Diabetic Retinopathy Among Chinese Hui Population. | 0 |
| 31602702 | 2020 | DNA hypermethylation is associated with invasive phenotype of malignant melanoma. | 29 |
| 31976761 | 2020 | Associations of rs2300782 CAMK4, rs2292239 ERBB3 and rs10491034 ARHGAP22 with Diabetic Retinopathy Among Chinese Hui Population. | 0 |
| 28544509 | 2017 | Association of ARHGAP22 gene polymorphisms with the risk of type 2 diabetic retinopathy. | 0 |
| 28544509 | 2017 | Association of ARHGAP22 gene polymorphisms with the risk of type 2 diabetic retinopathy. | 0 |
| 22952583 | 2012 | The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 has 1:2 stoichiometry and a single peptide binding mode. | 5 |
| 22952583 | 2012 | The weak complex between RhoGAP protein ARHGAP22 and signal regulatory protein 14-3-3 has 1:2 stoichiometry and a single peptide binding mode. | 5 |
| 21310492 | 2011 | Genome-wide association study of diabetic retinopathy in a Taiwanese population. | 58 |
| 21926414 | 2011 | The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2. | 49 |
| 21969604 | 2011 | Identification of RhoGAP22 as an Akt-dependent regulator of cell motility in response to insulin. | 7 |
| 21310492 | 2011 | Genome-wide association study of diabetic retinopathy in a Taiwanese population. | 58 |
| 21926414 | 2011 | The X-linked intellectual disability protein IL1RAPL1 regulates excitatory synapse formation by binding PTPδ and RhoGAP2. | 49 |
Citation
Dessen P
ARHGAP22 (Rho GTPase activating protein 22)
Atlas Genet Cytogenet Oncol Haematol. 2006-10-01
Online version: http://atlasgeneticsoncology.org/gene/43138/arhgap22
