ARMC8 (armadillo repeat containing 8)

2003-12-01  

Identity

HGNC
LOCATION
3q22.3
LOCUSID
ALIAS
GID5,HSPC056,S863-2,VID28
FUSION GENES

Other Information

Locus ID:

NCBI: 25852
MIM: 618521
HGNC: 24999
Ensembl: ENSG00000114098

Variants:

dbSNP: 25852
ClinVar: 25852
TCGA: ENSG00000114098
COSMIC: ARMC8

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000114098ENST00000358441Q8IUR7
ENSG00000114098ENST00000461600C9JAA7
ENSG00000114098ENST00000461822Q8IUR7
ENSG00000114098ENST00000463485C9J2I1
ENSG00000114098ENST00000464181H7C4J4
ENSG00000114098ENST00000466749C9J8P8
ENSG00000114098ENST00000468560C9J625
ENSG00000114098ENST00000469044Q8IUR7
ENSG00000114098ENST00000469860H7C5B7
ENSG00000114098ENST00000470549H7C5H2
ENSG00000114098ENST00000470821G5E9V6
ENSG00000114098ENST00000471453Q8IUR7
ENSG00000114098ENST00000471709C9JBY2
ENSG00000114098ENST00000481646Q8IUR7
ENSG00000114098ENST00000485396B7Z637
ENSG00000114098ENST00000489213G5E9V7
ENSG00000114098ENST00000491704Q8IUR7
ENSG00000114098ENST00000538260Q8IUR7

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
174671962007RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8alpha and ARMC8beta are components of the CTLH complex.48
248946752014ARMC8α promotes proliferation and invasion of non-small cell lung cancer cells by activating the canonical Wnt signaling pathway.8
269440572016Armc8 regulates the invasive ability of hepatocellular carcinoma through E-cadherin/catenin complex.6
251196012014Armc8 expression was elevated during atypia-to-carcinoma progression and associated with cancer development of breast carcinoma.4
260816212015ARMc8 indicates aggressive colon cancers and promotes invasiveness and migration of colon cancer cells.4
262328632015A novel biomarker ARMc8 promotes the malignant progression of ovarian cancer.4
277125952016Armadillo Repeat-Containing Protein 8 (ARMC8) Silencing Inhibits Proliferation and Invasion in Osteosarcoma Cells.4

Citation

Dessen P

ARMC8 (armadillo repeat containing 8)

Atlas Genet Cytogenet Oncol Haematol. 2003-12-01

Online version: http://atlasgeneticsoncology.org/gene/40884/armc8