ASAP2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2)

2014-11-01  

Identity

HGNC
ASAP2
LOCATION
2p25.1
LOCUSID
8853
ALIAS
AMAP2,CENTB3,DDEF2,PAG3,PAP,Pap-alpha,SHAG1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8853
MIM: 603817
HGNC: 2721
Ensembl: ENSG00000151693

Variants:

dbSNP: 8853
ClinVar: 8853
TCGA: ENSG00000151693
COSMIC: ASAP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000151693ENST00000281419O43150
ENSG00000151693ENST00000315273O43150
ENSG00000151693ENST00000641030A0A286YFG8

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Fc gamma R-mediated phagocytosisKEGGko04666
Fc gamma R-mediated phagocytosisKEGGhsa04666

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
152318472004A novel mode of action of an ArfGAP, AMAP2/PAG3/Papa lpha, in Arf6 function.17
209446572011Replication of top markers of a genome-wide association study in multiple sclerosis in Spain.8

Citation

Dessen P

ASAP2 (ArfGAP with SH3 domain, ankyrin repeat and PH domain 2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/60547/asap2