Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 25842
MIM: 609189
HGNC: 20995
Ensembl: ENSG00000111875
Variants:
dbSNP: 25842
ClinVar: 25842
TCGA: ENSG00000111875
COSMIC: ASF1A
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000111875 | ENST00000229595 | Q9Y294 |
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38561384 | 2024 | Identification of ASF1A and HJURP by global H3-H4 histone chaperone analysis as a prognostic two-gene model in hepatocellular carcinoma. | 0 |
| 38561384 | 2024 | Identification of ASF1A and HJURP by global H3-H4 histone chaperone analysis as a prognostic two-gene model in hepatocellular carcinoma. | 0 |
| 35136069 | 2022 | Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. | 9 |
| 35177609 | 2022 | RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity. | 6 |
| 35472331 | 2022 | Histone chaperone ASF1 acts with RIF1 to promote DNA end joining in BRCA1-deficient cells. | 7 |
| 36184659 | 2022 | Histone chaperone ASF1A accelerates chronic myeloid leukemia blast crisis by activating Notch signaling. | 3 |
| 35136069 | 2022 | Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. | 9 |
| 35177609 | 2022 | RIF1-ASF1-mediated high-order chromatin structure safeguards genome integrity. | 6 |
| 35472331 | 2022 | Histone chaperone ASF1 acts with RIF1 to promote DNA end joining in BRCA1-deficient cells. | 7 |
| 36184659 | 2022 | Histone chaperone ASF1A accelerates chronic myeloid leukemia blast crisis by activating Notch signaling. | 3 |
| 33503415 | 2021 | Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A. | 7 |
| 33576264 | 2021 | Elevated expression of ASF1B correlates with poor prognosis in human lung adenocarcinoma. | 12 |
| 33503415 | 2021 | Chk1 promotes non-homologous end joining in G1 through direct phosphorylation of ASF1A. | 7 |
| 33576264 | 2021 | Elevated expression of ASF1B correlates with poor prognosis in human lung adenocarcinoma. | 12 |
| 31744829 | 2020 | In Vivo Epigenetic CRISPR Screen Identifies Asf1a as an Immunotherapeutic Target in Kras-Mutant Lung Adenocarcinoma. | 95 |
Citation
Dessen P
ASF1A (anti-silencing function 1A histone chaperone)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/45707/asf1a
