Identity
HGNC
LOCATION
20q11.22
LOCUSID
ALIAS
AGSW,AGTI,AGTIL,ASP,SHEP9
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 434
MIM: 600201
HGNC: 745
Ensembl: ENSG00000101440
Variants:
dbSNP: 434
ClinVar: 434
TCGA: ENSG00000101440
COSMIC: ASIP
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000101440 | ENST00000374954 | P42127 |
| ENSG00000101440 | ENST00000568305 | P42127 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Melanogenesis | KEGG | ko04916 |
| Melanogenesis | KEGG | hsa04916 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36536132 | 2022 | Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity. | 6 |
| 36536132 | 2022 | Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity. | 6 |
| 28005267 | 2017 | Human gingiva transcriptome during wound healing. | 14 |
| 28005267 | 2017 | Human gingiva transcriptome during wound healing. | 14 |
| 25382380 | 2015 | Inherited variation at MC1R and ASIP and association with melanoma-specific survival. | 15 |
| 25705849 | 2015 | A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. | 45 |
| 25801600 | 2015 | SLC24A5 and ASIP as phenotypic predictors in Brazilian population for forensic purposes. | 4 |
| 25382380 | 2015 | Inherited variation at MC1R and ASIP and association with melanoma-specific survival. | 15 |
| 25705849 | 2015 | A Genome-Wide Association Study Identifies the Skin Color Genes IRF4, MC1R, ASIP, and BNC2 Influencing Facial Pigmented Spots. | 45 |
| 25801600 | 2015 | SLC24A5 and ASIP as phenotypic predictors in Brazilian population for forensic purposes. | 4 |
| 22628150 | 2013 | Variants at chromosome 20 (ASIP locus) and melanoma risk. | 14 |
| 22628150 | 2013 | Variants at chromosome 20 (ASIP locus) and melanoma risk. | 14 |
| 22447455 | 2012 | MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas. | 10 |
| 22447455 | 2012 | MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas. | 10 |
| 21221757 | 2011 | ASIP genetic variants and the number of non-melanoma skin cancers. | 3 |
Citation
Dessen P
ASIP (agouti signaling protein)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/714/asip
